Identification of Biomarkers in Spinocerebellar Ataxia 3
NCT03885167 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 22
Last updated 2023-11-22
Summary
The purpose of this study is to examine the differences in cerebral spinal fluid (CSF) and blood of patients with spinocerebellar ataxias and healthy volunteers. The goal of this project is to identify new biomarkers that are useful for characterizing spinocerebellar ataxias and identify targets for treatment or prevention of this condition.
Conditions
- Spinocerebellar Ataxia Type 3
Interventions
- OTHER
-
Specimen Collection
No interventions take place as part of study participation- only specimen collection occurs for both cohorts.
Sponsors & Collaborators
-
National Institutes of Health (NIH)
collaborator NIH -
National Institute of Neurological Disorders and Stroke (NINDS)
collaborator NIH - lead OTHER
Principal Investigators
-
Henry Paulson, MD · University of Michigan
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-02-21
- Primary Completion
- 2023-01-04
- Completion
- 2023-01-04
Countries
- United States
Study Locations
More Related Trials
-
Refinement and Assessment of New Magnetic Resonance Imaging Technologies for Neurological Exams
NCT00739518 ·Status: COMPLETED ·Phase: NA
-
Biomarker for Friedreich's Ataxia (BioFridA)
NCT04548921 ·Status: UNKNOWN
-
Cohort Study of Clinical and Neuroimaging Characteristics for BPPV Patients in China
NCT06228196 ·Status: RECRUITING
-
Sport-Related Concussion Recovery in Athletes
NCT06852300 ·Status: ENROLLING_BY_INVITATION
-
Multimodal Markers of Neurodegenerative Disorders at Presymptomatic Stages
NCT06516016 ·Status: NOT_YET_RECRUITING
-
Evaluating Cerebrospinal Fluid Biomarkers in Alzheimer's, Progressive Supranuclear Palsy Subjects, and Controls
NCT01348061 ·Status: COMPLETED
-
Prognostic Value of Three New Biomarkers of Multiple Sclerosis in Patients With Radiologically Isolated Syndrome
NCT03357887 ·Status: COMPLETED
-
Novel MRI Biomarkers for Monitoring Disease Progression in ALS
NCT03362658 ·Status: ACTIVE_NOT_RECRUITING
-
Evaluation and Validation of a Multimodal Brain Function Biomarker With NPC
NCT04074486 ·Status: COMPLETED
-
Mild Traumatic Brain Injury Registry
NCT01688869 ·Status: COMPLETED
-
Assessment of Cerebrospinal Fluid Flow Related Disorders Using a Phase-contrast Magnetic Resonance Imaging Technique.
NCT03656016 ·Status: RECRUITING
-
Clinical Evaluation of a Novel Balance, Vestibular and Oculomotor Assessment Tool
NCT02171312 ·Status: COMPLETED
-
Efficacy and Safety of Rituximab in the Treatment of Anti-Vimentin Antibody-associated Diseases
NCT07051070 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
A National Retrospective Population Based Cohort Study of the Natural History of Ataxia Telangiectasia
NCT04991701 ·Status: UNKNOWN
-
A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of [18F]NAV4694 PET for Detection of Cerebral Beta-Amyloid When Compared With Postmortem Histopathology
NCT01886820 ·Status: UNKNOWN ·Phase: PHASE3
-
A Prospective Longitudinal Study in Adults With Multifocal Motor Neuropathy
NCT05988073 ·Status: ACTIVE_NOT_RECRUITING
-
Vestibular Consequences of Blast-related Mild Traumatic Brain Injury (TBI)
NCT01021137 ·Status: COMPLETED
-
Use of in Vivo 3T MR to Characterize Carotid Plaque in Patients and Correlate MR Findings With Symptoms
NCT02335567 ·Status: COMPLETED
-
The Role of the Coagulation Pathway at the Synapse in Prion Diseases
NCT02480725 ·Status: UNKNOWN
-
Neuromelanin MRI: A Progression Marker in Early PD
NCT05631158 ·Status: UNKNOWN
-
EEG Diagnostic for Repetitive Sub-concussive Head Impacts
NCT05562544 ·Status: COMPLETED
-
Blood-Brain Barrier Disruption in People With White Matter Hyperintensities Who Have Had a Stroke
NCT03366129 ·Status: COMPLETED
-
Estimating Brain Biomechanics Using MRI
NCT01633268 ·Status: COMPLETED
-
Imaging Blood Brain Imaging Dysfunction in Parkinson's Disease
NCT02605161 ·Status: COMPLETED
-
The Effect of OMT on Functional Outcomes and Anti-inflammatory Biomarkers in Mild to Moderate Traumatic Brain Injury
NCT03163901 ·Status: COMPLETED ·Phase: NA