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Emotion Study/Substudy: Flexible Brain Study

NCT03872414 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 46

Last updated 2023-05-17

No results posted yet for this study

Summary

The proposed research applies the highly innovative technology of real-time functional Magnetic Resonance Imaging (rtfMRI) to examine plasticity of brain-regulatory mechanisms related to cognitive and affective processing and to determine benefits for cognition and affect in young and older adults and in Parkinson Disease (PD) patients.

Conditions

  • Aging
  • Emotions
  • Parkinson Disease

Interventions

BEHAVIORAL

Anterior cingulate cortex activation

Functional Magnetic Resonance Imaging Participants in the experimental group will be trained using functional magnetic resonance imaging to regulation brain activity in anterior cingulate cortex. The anterior cingulate cortex is a brain region that is known to be involved in emotion processing. Activation of this region is expected to improve emotion processing.

BEHAVIORAL

Primary auditory cortex activation

Functional Magnetic Resonance Imaging Participants in each group will be trained using functional magnetic resonance imaging to regulation brain activity in primary auditory cortex. The primary auditory cortex is a brain region that is NOT specifically involved in emotion processing. Activation of this region is NOT expected to improve emotion processing; and thus activation of this brain region serves as "control/placebo" condition in the current design (placebo comparator).

Sponsors & Collaborators

  • National Institute on Aging (NIA)

    collaborator NIH

  • Florida Department of Health

    collaborator OTHER_GOV

  • National Center for Advancing Translational Sciences (NCATS)

    collaborator NIH

  • University of Florida

    lead OTHER

Principal Investigators

  • Natalie Ebner, PhD · University of Florida, Department of Psychology

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-04-01
Primary Completion
2023-05-08
Completion
2023-05-08

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03872414 on ClinicalTrials.gov