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Predicting Outcomes of Cardiac Surgery-associated Acute Kidney Injury Using Biomarkers At Initiation of RRT

NCT03856723 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1200

Last updated 2022-06-01

No results posted yet for this study

Summary

The aim of this study was to verify the prognostic value of functional kidney biomarkers on survival and renal function recovery in cardiac surgery patients with acute kidney injury.

Conditions

Interventions

OTHER

Renal Replacement Therapy

Indications for RRT were defined as previously reported. 1. Kidney Disease: Improving Global Outcomes (KDIGO) stage 2 ; 2. severe sepsis, persistence of hypotension (for more than 6 h) despite preload optimization and use of vasopressors or catecholamines (norepinephrine or epinephrine \>0.1 μg/kg/min), 3. refractory fluid overload (worsening pulmonary edema, PaO2/FiO2 \<300 mm Hg or fluid balance \>10% of body weight), 4. low probability of rapid renal recovery according to the judgment of the intensivists and nephrologists.

Sponsors & Collaborators

  • Shanghai Zhongshan Hospital

    lead OTHER

Principal Investigators

  • Zhe Luo, PhD · Fudan University

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-03-01
Primary Completion
2024-12-31
Completion
2024-12-31

Countries

  • China

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03856723 on ClinicalTrials.gov