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Polymorphisms, Caffeine and Sleep Disorders

NCT03855774 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1100

Last updated 2019-02-28

No results posted yet for this study

Summary

Screening of a population of volunteer workers recruited on the occasion of their occupational health visit, within the Ministry of Defense and civil enterprises.

The voluntary subjects included will, after signing a consent, take a saliva sample (Kit Oragen DNA OG500) and fill out a computerized questionnaire.

A posteriori, the genotyping polymorphisms may be associated with variations in the pharmacokinetics or pharmacodynamics of caffeine will be achieved.

The primary objective is to determine whether polymorphisms (alone or in combination) of genes associated with the pharmacokinetics or pharmacodynamics of caffeine are independent risk factors for sleep disorders.

The secondary objectives are to determine the frequency of these polymorphisms and to evaluate the consequences of these associations on sleep habits (sleep time, chronotype, quality of sleep), daytime sleepiness, caffeine consumption, antecedents of accidents at work or traffic, drug consumption ...

Conditions

  • Polymorphism
  • Sleep Disorder
  • Coffee-Workers' Disease

Interventions

GENETIC

Polymorphisms

Classification of sleep disorders using 22 genetic polymorphisms

Sponsors & Collaborators

  • Institut de Recherche Biomedicale des Armees

    lead OTHER_GOV

Study Design

Allocation
NA
Purpose
SCREENING
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-01-01
Primary Completion
2018-01-01
Completion
2018-12-01

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03855774 on ClinicalTrials.gov