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Validation of a Non-Motor Fluctuation Assessment Instrument (NoMoFA) for Parkinson's Disease

NCT03845634 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 202

Last updated 2020-07-08

No results posted yet for this study

Summary

Investigators have developed a comprehensive questionnaire that assesses the presence of non-motor fluctuations (NMFs) in individuals with Parkinson's disease (PD). To date, 189 participants with PD have been assessed for preliminary data analysis prior to developing the penultimate version. At this time the objectives are to: (i) assess the scale's internal consistency and item-to-total correlations; (ii) assess test-retest reliability; (iii) use factor analysis and reliability measures to guide item reduction; (iv) assess construct validity; and (v) assess the scales ability to discriminate between static non-motor symptoms and non-motor symptoms which fluctuate (vi) estimate the relative distribution of cognitive, psychiatric, autonomic, sleep and sensory NMFs in PD patients with motor fluctuations and their impact on quality of life in Parkinson's disease.

Conditions

  • Parkinson Disease

Sponsors & Collaborators

  • University of Cincinnati

    collaborator OTHER

  • The Cleveland Clinic

    collaborator OTHER

  • University Health Network, Toronto

    collaborator OTHER

  • University of Michigan

    collaborator OTHER

  • Rush University

    collaborator OTHER

  • The Parkinson Study Group

    collaborator NETWORK

  • Assistive Technology Clinic, Canada

    lead OTHER

Principal Investigators

  • Galit Kleiner, MD · Assistive Technology Clinic

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-09-13
Primary Completion
2019-09-11
Completion
2019-09-11

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03845634 on ClinicalTrials.gov