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Preoperative Dose of Co-amoxiclav for Prevention of Postoperative Complications in Dentoalveolar Surgery

NCT03844776 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 135

Last updated 2020-10-06

No results posted yet for this study

Summary

There was no evidence to judge the effects of preventative antibiotics for extractions of severely decayed teeth, teeth in diseased gums, or extractions in patients who are sick or have low immunity to infection. Undertaking research in these groups of people may not be possible or ethical. However, it is likely that in situations where patients are at a higher risk of infection that preventative antibiotics may be beneficial, because infections in this group are likely to be more frequent and more difficult to treat To the best of knowledge, no adult study has compared the effects of single dose of Co-Amoxiclave and full oral course before or after dentoalveolar surgery. The current study has formally considered this comparison as a potential valuable trail for reducing the postoperative complications in adult patients who have had surgical removal of teeth under LA.

Conditions

Interventions

DRUG

Co-Amoxiclav

amoxicillin + clavulanic acid orally

DRUG

Paracetamol

paracetamol orally

DRUG

Chlorhexidine mouthwash

0.2% chlorhexidine mouthwash

DRUG

Normal saline

0.9% normal saline irrigation

DRUG

Amoxicillin 500 Mg

Amoxicillin 500 orally

DRUG

Metronidazole

metronidazole 500 mg orally

Sponsors & Collaborators

  • Taibah University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
SINGLE_GROUP

Eligibility

Min Age
16 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-10-02
Primary Completion
2020-12-02
Completion
2021-01-20

Countries

  • Saudi Arabia

Study Locations

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Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03844776 on ClinicalTrials.gov