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Exercise-induced Ischemia and the Influence of Pain Modulation in a Nerve Growth Factor (NGF) Model

NCT03844243 · Status: UNKNOWN · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2019-02-18

No results posted yet for this study

Summary

The purpose of this study is to investigate responses of pain and the maintenance of mechanical muscle hypersensitivity following an acute exercise-induced ischemic condition repeated over time in a prolonged NGF-sensitized muscle. Additionally, the influence of the pain modulating system on prolonged NGF muscle hypersensitivity caused by peripheral mechanisms and central mechanisms will also be investigated.

Conditions

  • Pain Response
  • Hyperalgesia
  • Healthy Subjects

Interventions

DRUG

NGF

Intramuscular injection

DRUG

Isotonic-saline

Intramuscular injection

Sponsors & Collaborators

  • Aalborg University

    lead OTHER

Principal Investigators

  • Line Bay Sørensen, PhD. stud. · Aalborg University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-02-18
Primary Completion
2019-06-30
Completion
2019-06-30

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03844243 on ClinicalTrials.gov