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Mechanisms of Tissue Repair After Muscle Injury and Tendon Strain

NCT05809947 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2024-01-09

No results posted yet for this study

Summary

The study is a 5-week human study including 24 18-35 year old healthy men. Each participant will have muscle injury and tendon strain induced in one leg using neuromuscular electrical stimulation in conjunction with forced lengthening contractions. The investigators will monitor the recovery from injury/strain over a 4 week period, in which half of the subjects will receive growth hormone (somatropin) to stimulate the connective tissue synthesis.

Conditions

  • Muscle; Injury, Quadriceps (Thigh)
  • Tendon Strain

Interventions

OTHER

Neuromuscular electrical stimulation

One bout of neuromuscular electrical stimulation in conjunction with forced lengthening contractions on one leg

Sponsors & Collaborators

  • Bispebjerg Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-04-11
Primary Completion
2024-01-03
Completion
2024-01-03

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05809947 on ClinicalTrials.gov