Outcome of Resection for Colorectal Cancer

Summary

There are limited data from retrospective studies regarding whether short-term and long-term outcomes after laparoscopic or robot-assisted radical colectomy (minimally invasive surgery) are equivalent to those after open abdominal radical colectomy (open surgery) among patients with early and medium-stage colorectal cancer.

This trial is a multicenter,prospective, randomized trial evaluating short-term and survival outcomes concerning minimally invasive surgery and open surgery for colorectal cancer.

Conditions

• Laparoscopy

Interventions

PROCEDURE

minimally invasive surgery

Each participating site required accreditation by the trial management committee to ensure proper surgical technique during minimally invasive surgery. No individual surgeons performed only the open approach or only the minimally invasive approach. The committee members reviewed the patients' outcomes and the videos to ensure the adequacy of the surgeon's technique.

Sponsors & Collaborators

• Qilu Hospital of Shandong University

  collaborator OTHER

• Zhejiang University

  collaborator OTHER

• Peking University Cancer Hospital & Institute

  collaborator OTHER

• Zhengzhou University

  collaborator OTHER

• Peking Union Medical College

  collaborator OTHER

• Sun Yat-sen University

  collaborator OTHER

• Fudan University

  collaborator OTHER

• Shanghai Jiao Tong University School of Medicine

  collaborator OTHER

• Massachusetts General Hospital

  collaborator OTHER

• Harvard Medical School (HMS and HSDM)

  collaborator OTHER

• M.D. Anderson Cancer Center

  collaborator OTHER

• University of California, Los Angeles

  collaborator OTHER

• University of Pennsylvania

  collaborator OTHER

• Tianjin Medical University Cancer Institute and Hospital

  lead OTHER

Principal Investigators

• Dalu M Kong, M.D. · Tianjin Medical University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

90 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-02-15

Primary Completion

2019-11-30

Completion

2026-12-31

Countries

• China

Study Locations