MedTrace Logo

Inflammatory Mediators as Potential Non-Invasive Biomarkers in Subjects With Eosinophilic Esophagitis

NCT03822325 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 88

Last updated 2024-11-15

No results posted yet for this study

Summary

The investigators seek to assess esophageal inflammation or lack of it in response to treatment with a novel non-invasive method that would measure eosinophil-associated inflammatory mediators in the blood and urine to determine the presence of active Eosinophilic Esophagitis. For these purposes, the investigators will correlate esophageal inflammatory mediators measured in blood and urine with histological findings identified on esophageal mucosal biopsies. Additionally, biopsies associated mediators will be assessed relative to clinical phenotype and outcome.

Conditions

  • Eosinophilic Esophagitis

Sponsors & Collaborators

  • Ann & Robert H Lurie Children's Hospital of Chicago

    lead OTHER

Principal Investigators

  • Joshua Wechsler, MD · Ann & Robert H Lurie Children's Hospital of Chicago

  • Barry Wershil, MD · Ann & Robert H. Lurie Children's Hospital fo Chicago

Eligibility

Min Age
1 Year
Max Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-02-28
Primary Completion
2015-05-31
Completion
2025-11-30

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03822325 on ClinicalTrials.gov