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Food Antigen in Eosinophilic Esophagitis

NCT02434705 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 72

Last updated 2023-12-12

No results posted yet for this study

Summary

The relationship or effect of food antigen (wheat based soy sauce) in eosinophilic esophagitis. It is believed that when food antigens are exposed to the esophageal tissue it starts an chronic allergy-based inflammation. This will be analyzed with the esophageal biopsies and the mucosal impedance probe.

Conditions

  • Eosinophilic Esophagitis

Interventions

OTHER

Antigen (wheat base soy sauce) spray

Patients having a clinically indicated endoscopy for Eosinphilic Esophagitis will have two biopsies from the esophageal body, 10 cm above the gastroesophageal junction. After biopsies are taken, approximately 10 cc of wheat based soy sauce will be sprayed though an endoscopic catheter onto the esophageal mucosa. The endoscopic examination will be completed and Two additional endoscopic biopsies will be taken 10 cm above the gastroesophageal junction.

Sponsors & Collaborators

Principal Investigators

  • Joseph Murray, MD · Mayo Clinic

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-04-01
Primary Completion
2023-12-08
Completion
2023-12-08

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02434705 on ClinicalTrials.gov