The Effect of 12-week Dietary Intake of Syrup Containing CoQ10 and Collagen on Dermis Density and Other Skin Parameters

Summary

Placebo controlled double-blind multi-dose comparative study of the effects of coenzyme Q10 and collagen formulation with improved water-solubility in healthy adults.

One group (test group) will receive investigational product - test syrup (daily dose 10 mL: fish collagen: 4000 mg, water soluble CoQ10 (Q10Vital®): 50 mg, vitamin C: 80 mg, vitamin A: 920 μg, biotin: 150 μg) and the other (placebo group) placebo syrup without those active ingredients. Participants will test continuous administration of placebo or investigational product for 12 weeks in order to demonstrate and assess multiple-dose effects on skin condition and signs of skin aging.

Conditions

• Dermis Density
• Trans Epidermal Water Loss (TEWL)
• Skin Hydration
• Wrinkles
• Dermis Thickness

Interventions

DIETARY_SUPPLEMENT

Test syrup containing CoQ10 and collagen

Test group will receive investigational product - test syrup (daily dose 10 mL: fish collagen: 4000 mg, water soluble CoQ10 (Q10Vital®): 50 mg, vitamin C: 80 mg, vitamin A: 920 μg, biotin: 150 μg); continuous administration of investigational product for 12 weeks.

DIETARY_SUPPLEMENT

Placebo syrup

Placebo group will receive placebo syrup without active ingredients. (daily dose 10 mL: fish collagen: 0 mg, water soluble CoQ10 (Q10Vital®): 0 mg, vitamin C: 0 mg, vitamin A: 0 μg, biotin: 0 μg); continous administration of placebo product for 12 weeks.

Sponsors & Collaborators

• European Regional Development Fund

  collaborator OTHER

• Valens Int. d.o.o., Slovenija

  collaborator INDUSTRY

• Ministry of Education, Science and Sport, Republic of Slovenia

  collaborator UNKNOWN

• VIST - Faculty of Applied Sciences

  lead OTHER

Principal Investigators

• Katja Žmitek, PhD · Head of Reasearch Group

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Model

PARALLEL

Eligibility

Min Age

40 Years

Max Age

65 Years

Sex

FEMALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2018-10-15

Primary Completion

2019-02-19

Completion

2019-07-10

Countries

• Slovenia

Study Locations