The Effect of 16-week Dietary Intake of Food Supplements Containing Collagen and MSM on Skin

Summary

The aim of the study is to compare the effects of multiple-dose 16 weeks daily dietary supplementation with 5 g or 3 g of collagen in combination with 1 g or 1.5 g of MSM and 80 mg vitamin C (see 1.2. Investigational and placebo product profile) on skin in healthy human subjects in comparison to placebo product. The main objective is to show that test products have beneficial effects on dermis density, and also on other skin parameters and to investigate differences in the effects among test products.

Conditions

• Dermis Density
• Wrinkles
• Dermis Thickness
• Skin Texture
• Skin Elasticity
• Skin Redness

Interventions

DIETARY_SUPPLEMENT

ColMSM-HL

Participants will test continuous administration of investigational product for 16 weeks.

DIETARY_SUPPLEMENT

Placebo syrup

Participants will test continuous administration of placebo product for 16 weeks.

DIETARY_SUPPLEMENT

ColMSM-LH

Participants will test continuous administration of investigational product for 16 weeks.

DIETARY_SUPPLEMENT

ColMSM-LL

Participants will test continuous administration of investigational product for 16 weeks.

DIETARY_SUPPLEMENT

Col-L

Participants will test continuous administration of investigational product for 16 weeks.

Sponsors & Collaborators

• Tosla d.o.o.

  collaborator INDUSTRY

• Slovenian Research and Innovation Agency

  collaborator UNKNOWN

• VIST - Faculty of Applied Sciences

  lead OTHER

Principal Investigators

• Katja Žmitek, PhD · Head of Reasearch Group

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Model

PARALLEL

Eligibility

Min Age

40 Years

Max Age

65 Years

Sex

FEMALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2025-01-27

Primary Completion

2025-06-17

Completion

2025-06-17

Countries

• Slovenia

Study Locations