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Effect of Topical Sulforaphane on Skin Aging and With Ultraviolet and Visible Light Exposure

NCT03730649 · Status: ACTIVE_NOT_RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2025-09-26

No results posted yet for this study

Summary

The study is to compare the expression of both keratin 16 and 17 before and after application of sulforaphane on both photoprotected and photoexposed area, and to determine whether these findings alter skin aging as well as skin response to ultraviolet (UV) and visible light exposure.

Conditions

  • Skin Aging

Interventions

DRUG

Sulforaphane (broccoli sprout extract)

Participants will topically apply Sulforaphane for a period of time

RADIATION

UV or visible light

Participants will have 2 test areas irradiated with up to 5 UV or visible light treatments

Sponsors & Collaborators

Principal Investigators

  • Anna Chien · Department of Dermatology, Johns Hopkins School of Medicine

Study Design

Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-10-09
Primary Completion
2025-03-01
Completion
2026-10-31
FDA Drug
Yes

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03730649 on ClinicalTrials.gov