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Preoperative Risk Factors and Perioperative Neurocognitive Disorders

NCT03805685 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 38

Last updated 2024-12-06

No results posted yet for this study

Summary

Perioperative neurocognitive disorders (PND's) remain an important complication after surgery. After many years of speculating about the etiology of this complication, currently studies are pointing to an inflammatory cascade being set in motion.

This prospective study is designed to examine preoperative lifestyle factors (such as sedentary behavior) associated with postoperative cognitive impairment in a group of patients undergoing non-cardiac surgery.

The objectives in our study are to:

identify perioperative risk factors for the development of PND's measure the incidence and duration of perioperative neurocognitive disorders in a known high-risk group of elective surgical patients measure a peripheral inflammatory marker (interleukin 6: IL-6) in the same group of surgical patients

Conditions

  • Cognitive Change

Interventions

PROCEDURE

Non-Cardiac Surgery

Non-cardiac surgery

Sponsors & Collaborators

  • CHU de Charleroi

    collaborator OTHER

  • Université Libre de Bruxelles

    lead OTHER

Principal Investigators

  • Jean Boogaerts, MD; PhD · Université Libre de Bruxelles

Eligibility

Min Age
55 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-03
Primary Completion
2019-09-25
Completion
2019-10-30

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03805685 on ClinicalTrials.gov