Prevalence of Primary Aldosteronism in Patients With Stroke

NCT03789357 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2022-05-20

No results posted yet for this study

Summary

Strokes leads to significant morbidity and mortality, and hypertension is the most important risk factor for strokes. It is estimated that up to 10% of patients with hypertension have the underlying, treatable condition of primary aldosteronism. Hence, we hypothesize that the prevalence of primary aldosteronism is high in patients with strokes, a complication of long-standing hypertension.

Patients admitted with an acute stroke to the Acute Stroke Unit, Changi General Hospital, will be screened for Primary Aldosteronism three months post-stroke, and confirmatory tests will be done with saline-infusion test.

Conditions

  • Primary Aldosteronism
  • Stroke

Interventions

DIAGNOSTIC_TEST

Aldosterone renin ratio

Aldosterone Renin Ratio to screen for Primary Aldosteronism

Sponsors & Collaborators

  • Changi General Hospital

    lead OTHER

Principal Investigators

  • Troy Puar, MRCP UK · Changi General Hospital

Eligibility

Min Age
21 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-05-01
Primary Completion
2021-07-31
Completion
2021-09-30

Countries

  • Singapore

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03789357 on ClinicalTrials.gov