The 90% Effective Dose of Nalbuphine in Mechanical Ventilated Patients in the ICU
NCT03786887 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2018-12-26
Summary
The aim of this study is to determine the effective nalbuphine dose in 90% of intubated patients in the ICU, including the continuous infusion dose and a bolus dose during moving to the lateral decubitus position. Pain will assessed using a Behavioural Pain Scale (BPS) requiring a score of 3-4.
Conditions
Interventions
- DRUG
-
Nalbuphine
dosage of nalbuphine
Sponsors & Collaborators
-
Hua-Qing Shu
lead OTHER
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-10-24
- Primary Completion
- 2019-10-31
- Completion
- 2019-10-31
Countries
- China
Study Locations
More Related Trials
-
Pharmacokinetic Study of Single and Multiple Intravenous Administration of Nalbuphine Hydrochloride Injection in Healthy Chinese Volunteers
NCT06902103 ·Status: COMPLETED ·Phase: PHASE1
-
The Optimization of Procedural Pain Control in Intensive Care Unit (ICU) Patients
NCT00558090 ·Status: COMPLETED ·Phase: NA
-
Intravenous Buprenorphine Versus Morphine for Severe Pain in the Emergency Department
NCT03256487 ·Status: UNKNOWN ·Phase: PHASE2
-
Sublingual Sufentanil vs Intravenous Fentanyl for Acute Pain in the Ambulatory Surgery Center
NCT04177862 ·Status: COMPLETED ·Phase: PHASE4
-
The Role of Opioidergic Systems in Breathing Based Analgesia
NCT03419858 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Nebulized Morphine in Chest Trauma Patients: A Prospective Study
NCT03580187 ·Status: COMPLETED ·Phase: PHASE3
-
Pharmacokinetics of Nalbuphine Injection
NCT03826316 ·Status: COMPLETED ·Phase: PHASE4
-
Nalbuphine Versus Morphine for Mucositis Pain in Pediatric Cancer Patients
NCT03825887 ·Status: COMPLETED ·Phase: PHASE3
-
The Effects of Patient Features on Opioid Induced End-Tidal CO2
NCT01371903 ·Status: COMPLETED
-
Titrated Versus High and Low Dose Nebulized Morphine to Reduce Pain in Emergency Settings
NCT02200185 ·Status: COMPLETED ·Phase: NA
-
Adding Nalbuphine for Control of Intrathecal Morphine Pruritus
NCT04589429 ·Status: UNKNOWN ·Phase: PHASE2
-
Brain Response to Pain Control in People With Chronic Pain
NCT01878019 ·Status: COMPLETED
-
IV PCA With or Without Continuous Dose vs Oral Opioid to Maintain Analgesia for Severe Cancer Pain After Successful Titration
NCT04785768 ·Status: COMPLETED ·Phase: PHASE3
-
A Non-randomised, Non-inferiority Comparative Study of Oral Actiskenan (Morphine Sulfate) Versus Intranasal Sufentanil in the Early Management of Severe Acute Pain in Emergency Departments.
NCT07344350 ·Status: WITHDRAWN
-
Neurotoxic Adverse Effects of Morphine and Oxycodone for Pain in Terminal Patients With Diminished Renal Function
NCT03616639 ·Status: TERMINATED ·Phase: PHASE4
-
Morphine Titration by Patient Self-controlled by a Mechanical Device Versus Administration by the Nurse for Patients With Severe Acute Pain in the Emergency Department
NCT02152176 ·Status: COMPLETED ·Phase: PHASE4
-
Effectiveness and Feasibility of Patient Controlled Analgesia in the ED
NCT01775371 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Butorphanol Tartrate Injection for the Patients With Mechanical Ventilation
NCT05201560 ·Status: UNKNOWN ·Phase: NA
-
Inhaled vs IV Opioid Dosing for the Initial Treatment of Severe Acute Pain in the Emergency Department
NCT03257319 ·Status: COMPLETED ·Phase: PHASE3
-
Reduced Opioid Analgesic Requirements Via Improved Endogenous Opioid Function
NCT02469077 ·Status: COMPLETED ·Phase: NA
-
First Evaluation of Morphine Hydrochloride by Nebulisation in Healthy Volunteers
NCT01975753 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Oxycodone/Naloxone (OXN) Combination in Moderate to Severe Non-malignant Pain
NCT01167127 ·Status: COMPLETED ·Phase: PHASE3
-
CO2 Monitoring Study
NCT02068274 ·Status: COMPLETED
-
Effectiveness and Tolerance of Inhaled Fentanyl Aerosol (25µg/Dose) in Chinese Patients With Breakthrough Cancer Pain
NCT04713189 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Ultra-low Dose Oral Ketamine for Chronic Pain in the Primary Care Setting
NCT02303847 ·Status: UNKNOWN ·Phase: PHASE3