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Prevention of Post Traumatic Stress Disorder by Early Treatment

NCT00146900 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 298

Last updated 2016-02-19

No results posted yet for this study

Summary

To prospectively evaluate the effect of early treatment (cognitive therapy (CT), cognitive-behavioral therapy (CBT) and escitalopram (SSRI) in preventing the occurrence of post-traumatic stress disorder in recent survivors of traumatic events.

Conditions

  • Post-traumatic Stress Disorder

Interventions

PROCEDURE

Cognitive Behavioral Therapy

12 weekly 1.5 hours weekly session of cognitive behavioral therapy (Prolonged Exposure)

PROCEDURE

Cognitive Therapy

12 weekly 1.5 hours weekly session of cognitive therapy without exposure

DRUG

Escitalopram

Twelve weeks of treatment with Escitalopram at Max. daily dose of 20mg

OTHER

Placebo

Twelve weeks of treatment with placebo pills resembling the original Escitalopram 10mg tablets but containing no active substance

Sponsors & Collaborators

  • Hadassah Medical Organization

    lead OTHER

Principal Investigators

  • Arieh Y Shalev, M.D. · Hadassah Medical Organization

  • Yossi Israeli - Shalev, M.A. · Hadassah Medical Organization

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-08-31
Primary Completion
2008-01-31
Completion
2008-01-31

Countries

  • Israel

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00146900 on ClinicalTrials.gov