Strategies to Improve Pain and Enjoy Life

Summary

In the Strategies to Improve Pain and Enjoy Life (STRIPE) study, the effectiveness of a multicomponent intervention will be tested, compared with usual care, on opioid dose and pain outcomes among patients on high dose (≥ 40 mg morphine equivalent dose) long-term opioid therapy in a randomized controlled trial. This intervention will have 4 components: a) telephone-delivered evidence-based pain self-management training, b) web-based video of successfully tapered patients with motivational interviewing debriefing, c) a voluntary, self-paced opioid taper, and d) opioid and non-opioid prescribing guidance for the patient's primary care provider.

Conditions

• Chronic Pain

Interventions

BEHAVIORAL

Pain self-management training

This intervention will have 4 components: 1. telephone-delivered evidence-based pain self-management training, 2. web-based video of successfully tapered patients with motivational interviewing debriefing, 3. a voluntary, self-paced opioid taper 4. opioid and non-opioid prescribing guidance for the patient's primary care provider.

BEHAVIORAL

video education, motivational interviewing

web-based video of successfully tapered patients with motivational interviewing debriefing

BEHAVIORAL

voluntary self-paced opioid taper

Voluntary self-paced opioid taper where patient chooses whether, when and how much to taper opioids. Taper schedule and strategy will be proposed to patients, but they will negotiate details with their primary care provider.

BEHAVIORAL

prescribing guidance for primary care provider

Based upon review of medications and diagnoses in the electronic medical record, the principal investigator will offer guidance on opioid taper rate and strategy. He will also offer suggestions to adjust or initiate other psychotropic medications to treat pain or psychiatric comorbid illness that may be unmasked through opioid taper. All prescriptions will be written by the primary care provider.

OTHER

usual care

Usual care will consist of any and all regular care that may be offered by primary care for chronic pain and related illnesses

Sponsors & Collaborators

• Kaiser Permanente

  collaborator OTHER

• National Institute on Drug Abuse (NIDA)

  collaborator NIH

• University of Washington

  lead OTHER

Principal Investigators

• Mark D Sullivan, MD, PhD · University of Washington

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-04-04

Primary Completion

2022-01-27

Completion

2022-01-27

Countries

• United States

Study Locations