Serum Biomarkers for Portal Hypertension in Cirrhosis (Pan-CHESS1802)
NCT03713606 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 75
Last updated 2021-08-17
Summary
This is a prospective, multi-center diagnostic trial conducted at 6 liver centers in China designed to study the correlation between serum biomarkers associated with endothelial dysfunction and immune inflammation and hepatic venous pressure gradient in cirrhosis.
Conditions
- Hypertension, Portal
Interventions
- PROCEDURE
-
HVPG measurement
HVPG obtained by means of catheterization of a hepatic vein with a balloon catheter.
Sponsors & Collaborators
-
Beijing YouAn Hospital
collaborator OTHER -
Shandong Provincial Hospital
collaborator OTHER_GOV -
Beijing Shijitan Hospital, Capital Medical University
collaborator OTHER -
Beijing Friendship Hospital
collaborator OTHER -
Xingtai People's Hospital
collaborator OTHER -
Beijing 302 Hospital
collaborator OTHER -
Nanfang Hospital, Southern Medical University
lead OTHER
Principal Investigators
-
Xiaolong Qi, M.D. · Nanfang Hospital, Southern Medical University
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-09-30
- Primary Completion
- 2022-01-31
- Completion
- 2022-06-01
Countries
- China
Study Locations
More Related Trials
-
Evaluation of the Role of Plasma Biomarkers in the Development of Decompensation in Patients With Cirrhosis .
NCT03084185 ·Status: UNKNOWN
-
TIPS for PH Patients: an Observational, Cohort Study
NCT06221982 ·Status: RECRUITING
-
Noninvasive Prediction of Portal Hypertension in Cirrhosis Using Sound Touch Viscoelastography
NCT06316869 ·Status: NOT_YET_RECRUITING
-
Endoscopic Ultrasound-guided Measurement of Portal Vein Pressure Gradient
NCT07062289 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Pilot Study: Defining Peripheral Endothelial Function in Portal Hypertensive Cirrhotic Patients
NCT02356250 ·Status: WITHDRAWN
-
Establishment and Assessment of the HVPG Using Biofluid Mechanics (HVPGBFM)
NCT03470389 ·Status: UNKNOWN ·Phase: NA
-
WFA+M2BP in Evaluation of Portal Hypertension and Clinical Outcome in Patients With Liver Cirrhosis
NCT03195634 ·Status: UNKNOWN
-
Early Precise Diagnosis and Intervention of CPT Based on a Noninvasive 3D-vHPS
NCT02925975 ·Status: UNKNOWN ·Phase: PHASE4
-
Impact of Fentanyl Analgesia on the Accuracy of HVPG Measurements in Patients With Portal Hypertension
NCT04724148 ·Status: UNKNOWN ·Phase: NA
-
Effectiveness and Safety of TIPS Stent Graft in the Treatment of Cirrhosis and Complications of Portal Hypertension
NCT06669806 ·Status: RECRUITING ·Phase: NA
-
Early Diagnosis and Timely Treatment of Cirrhotic Patients With Minimal Hepatic Encephalopathy (CHESS-NCRCID 2106)
NCT05140837 ·Status: UNKNOWN
-
The Impact of Transjugular Intrahepatic Portosystemic Shunt on Recompensation in Patients With Decompensated Liver Cirrhosis
NCT07172035 ·Status: RECRUITING
-
Effect of Handgrip Strength on Portal Vein Hemodynamics in Patients With Liver Cirrhosis
NCT07116096 ·Status: RECRUITING ·Phase: NA
-
Effect of Transjugular Intrahepatic Portosystemic Shunt on Gut Microbiota in Cirrhotic Patients
NCT02427906 ·Status: UNKNOWN
-
Phase II/III Clinical Trial of Recombinant Human Serum Albumin in Cirrhotic Patients With Ascites
NCT06553456 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Validation of New Prognostic Biomarkers in Patients With Decompensated Cirrhosis
NCT06855056 ·Status: RECRUITING
-
Portal Hypertension and Systemic Endothelial Function
NCT02850692 ·Status: UNKNOWN ·Phase: NA
-
Non-invasive Method for Predicting the Presence of Gastroesophageal Varices in Patients With Cirrhosis
NCT04123509 ·Status: UNKNOWN
-
Prognosis Scoring System for Acute-on-Chronic Liver Failure
NCT01961440 ·Status: UNKNOWN
-
Endoscopic Ruler for the Assessment of Variceal Bleeding Risks (CHESS2005)
NCT04639323 ·Status: UNKNOWN
-
Utility of Renal Biomarkers in Cirrhosis
NCT01217983 ·Status: COMPLETED
-
The vPPG-detecting Software Guided Management of Cirrhotic Portal Hypertension
NCT04786782 ·Status: UNKNOWN
-
Surrogate Markers of Portal Pressure
NCT02508298 ·Status: COMPLETED ·Phase: NA
-
EUS Guided Portal-systemic Pressure Gradient Measurement
NCT04633356 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Safety of Discontinuing NSBBs in Cirrhotic Patients With Managed Primary Aetiological Factors
NCT06549673 ·Status: RECRUITING