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Milk Protein and Bone Health in Postmenopausal Women

NCT03701113 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2025-01-29

No results posted yet for this study

Summary

The process of bone remodeling exhibits pronounced diurnal pattern that is important for bone health. A balanced rate of bone resorption is required to maintain bone health, a balance that can be disturbed during the life-cycle to effect net rate of formation (as occurs during growth and development to adulthood) or net resorption (as occurs, for example, during the menopause). Bone turnover is a nutritionally modulated process and the investigators believe a milk-based protein supplement (MBPS) can modulate beneficially the rate of bone resorption over the time period when bone remodeling is most active i.e. late evening/overnight. In this novel approach to the timing of nutrient ingestion, the proposed nutrient intervention seeks to modify (reduce) the rate of bone resorption and promote the rate of bone formation to the benefit of bone health in this at risk population..

Conditions

  • Bone and Bones
  • Osteoporosis Risk
  • Osteoporosis, Postmenopausal

Interventions

DIETARY_SUPPLEMENT

Milk-based protein matrix (MBPM)

Ingestion of the Test Product at 10:00 pm, post-absorptive of the evening meal, each day for the 24 week period of intervention

DIETARY_SUPPLEMENT

Habitual dietary behaviour

Subjects to maintain habitual dietary behaviour for the 24 week intervention

Sponsors & Collaborators

  • Dairygold Cooperative Society

    collaborator UNKNOWN

  • University of Limerick

    lead OTHER

Principal Investigators

  • Philip M Jakeman, PhD · University of Limerick

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
70 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-10-22
Primary Completion
2019-07-30
Completion
2019-07-30

Countries

  • Ireland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03701113 on ClinicalTrials.gov