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Physiological Changes With High-Flow Nasal Cannula

NCT03700606 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2026-04-17

Study results available
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Summary

To measure changes in physiologic parameters in extremely low birthweight (ELBW) infants on high-flow nasal cannula compared to nasal continuous positive airway pressure (nCPAP).

Conditions

  • Respiratory Distress Syndrome in Premature Infant

Interventions

PROCEDURE

High flow nasal cannula

8 liters per minute of blended oxygen through Fisher Paykel Optiflow Jr 2 nasal prongs.

PROCEDURE

Nasal CPAP

Nasal continuous positive airway pressure of 5-7 cm/H20 delivered using Ventilator or bubble cpap device through short nasal prongs or a nasal face mask.

Sponsors & Collaborators

  • Sharp HealthCare

    lead OTHER

Principal Investigators

  • Anup Katheria, MD · Sharp HealthCare

Study Design

Allocation
NON_RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
23 Weeks
Max Age
28 Weeks
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-03-15
Primary Completion
2021-12-20
Completion
2022-02-14

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03700606 on ClinicalTrials.gov