Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules
NCT03676647 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 22
Last updated 2026-02-20
Summary
This trial studies how well the diagnostic deoxyribonucleic acid (DNA) methylation signature works in detecting thyroid cancer in patients with thyroid nodules. Using diagnostic testing, such as the diagnostic DNA methylation signature, may be a less invasive way to check for thyroid cancer.
Conditions
- Thyroid Gland Nodule
Interventions
- OTHER
-
Diagnostic DNA Methylation Signature
Undergo collection of tissue samples
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
City of Hope Medical Center
lead OTHER
Principal Investigators
-
Maria Hahn, PhD · City of Hope Medical Center
Eligibility
- Min Age
- 19 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-04-25
- Primary Completion
- 2028-09-25
- Completion
- 2028-09-25
Countries
- United States
Study Locations
More Related Trials
-
99mTc Sestamibi Scans In Thyroglobulin Positive Scan Negative Differentiated Thyroid Cancer (DTC) Patients
NCT03065218 ·Status: TERMINATED ·Phase: PHASE4
-
The Evaluation of the Diagnostic Properties of Intra-operative In-situ Thyroglobin Levels of Cervical Lymph Nodes, in the Discrimination Between Benign and Malignant Lymph Nodes in Thyroid Cancer: a Prospective Multicentre Study.
NCT02602717 ·Status: UNKNOWN ·Phase: NA
-
An Easy Sonographic Scoring System for Predicting Malignant Thyroid Nodules
NCT01307761 ·Status: UNKNOWN
-
Thyroglobulin Point of Care Assay for Rapid Detection of Metastatic Differentiated Thyroid Carcinoma
NCT05078853 ·Status: COMPLETED
-
Improved Preoperative Selection of Cold Thyroid Nodules
NCT00297297 ·Status: UNKNOWN
-
Study Of AG-013736 In Patients With 131I-Refractory Thyroid Cancer
NCT00389441 ·Status: COMPLETED ·Phase: PHASE2
-
PACE4 in Thyroid Cancer
NCT03160482 ·Status: COMPLETED
-
Identification of Molecular Biomarkers for Thyroid Cancer
NCT04133870 ·Status: UNKNOWN
-
PET Evaluation of Recurrent Differentiated Thyroid Cancer
NCT01641679 ·Status: UNKNOWN
-
microRNA in Thyroid Cancer
NCT01964508 ·Status: COMPLETED
-
Three-dimensional Thyroid Education Model
NCT06146998 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
The Role of Midkine in Diagnosis of Thyroid Cancer
NCT03978351 ·Status: UNKNOWN
-
Study of the Anti-angiogenesis Agent AG-013736 in Patients With Metastatic Thyroid Cancer
NCT00094055 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Collect Information About the Use of Redifferentiating Medications as a Standard Treatment for Thyroid Cancer
NCT05733013 ·Status: RECRUITING
-
Metabolic Effects of Synthetic Thyroid Hormone for Thyroid Cancer Treatment
NCT01441154 ·Status: COMPLETED
-
Biomarkers to Distinguish Benign From Malignant Thyroid Neoplasm
NCT01433809 ·Status: COMPLETED
-
Differentiation of Benign From Malignant Thyroid Nodules Using Diffuse Reflectance Spectroscopy
NCT07124065 ·Status: ACTIVE_NOT_RECRUITING
-
Decitabine in Treating Patients With Metastatic Papillary Thyroid Cancer or Follicular Thyroid Cancer Unresponsive to Iodine I 131
NCT00085293 ·Status: COMPLETED ·Phase: PHASE2
-
Circulating Biomarkers to Identify Thyroid Cancer
NCT04594720 ·Status: COMPLETED
-
The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer
NCT03841617 ·Status: RECRUITING ·Phase: PHASE2
-
3D Thyroid Education Model for Student
NCT06147011 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Radiofrequency Ablation in TIR3A Nodules With Negative Genetic Evaluation
NCT05765695 ·Status: RECRUITING ·Phase: NA
-
Study of Resistance to Thyroid Hormone After Long-term Exposure in People With Thyroid Cancer
NCT04868045 ·Status: WITHDRAWN ·Phase: PHASE1
-
Treatment for Patients With Metastatic Thyroid Cancer
NCT00176748 ·Status: COMPLETED ·Phase: PHASE2
-
Urinary Exosomal Biomarkers of Thyroglobulin and Galectin-3 for Prognosis and Follow-up in Patients of Thyroid Cancer
NCT04948437 ·Status: ACTIVE_NOT_RECRUITING