Urinary Exosomal Biomarkers of Thyroglobulin and Galectin-3 for Prognosis and Follow-up in Patients of Thyroid Cancer
NCT04948437 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 103
Last updated 2026-04-13
Summary
Now, the investigators carried out a prospective study enrolling patients with thyroid cancer, who had received ablative thyroidectomy and /or radioactive iodine therapy for two more years. The investigators' study already enrolled seventy-three patients with thyroid cancer, and the investigators plan to enroll 30 new patients in this consecutive research study. All patients received total thyroidectomy under clinically surgical judgement in initial therapeutic option. The investigators also further found some difference between papillary thyroid cancer and follicular thyroid cancer, and the investigators will continue annually to closely monitor the change of U-Ex Tg and urinary exosomal galectin-3 between differently cellular types of thyroid cancers.
Conditions
- Thyroid Cancer
- Papillary Thyroid Cancer
- Follicular Thyroid Cancer
Sponsors & Collaborators
-
National Taiwan University Hospital
lead OTHER
Principal Investigators
-
CHIH-YUAN WANG, Doctor · Department of Internal Medicine, National Taiwan University Hospital
Eligibility
- Min Age
- 20 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-08-19
- Primary Completion
- 2026-04-08
- Completion
- 2026-10-31
Countries
- Taiwan
Study Locations
More Related Trials
-
OnT4-Thyroglobulin Assay Before rhTSH-Aided Radioiodine Ablation
NCT00439127 ·Status: COMPLETED
-
Circulating Biomarkers to Identify Thyroid Cancer
NCT04594720 ·Status: COMPLETED
-
Long-term Survival Outcomes of Total Thyroidectomy and Radioactive Iodine Therapy in Unilateral T3/T4 FTC
NCT06437873 ·Status: COMPLETED
-
Recurrence in Patients With Differentiated Thyroid Cancer
NCT06154863 ·Status: NOT_YET_RECRUITING
-
Differentiated Thyroid Cancer Patients Treated With Different Doses of Radioactive Iodine.
NCT06134830 ·Status: NOT_YET_RECRUITING
-
Determination of Pronostics Factors for Advanced Thyroid Carcinoma (pT3 pT4 or M1 at Diagnosis)
NCT02156362 ·Status: UNKNOWN ·Phase: NA
-
Differentiation of Benign From Malignant Thyroid Nodules Using Diffuse Reflectance Spectroscopy
NCT07124065 ·Status: ACTIVE_NOT_RECRUITING
-
Long Non Coding RNA HOTAIR and Midkine as Biomarkers in Thyroid Cancer
NCT03469544 ·Status: UNKNOWN
-
Study of Resistance to Thyroid Hormone After Long-term Exposure in People With Thyroid Cancer
NCT04868045 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Study of AL2846 Capsule Versus Placebo in the Treatment of Advanced Radioiodine-Refractory Differentiated Thyroid Carcinoma
NCT06860971 ·Status: RECRUITING ·Phase: PHASE3
-
Outcome of RAI131 Therapy in Patients With Differentiated Thyroid Cancer (Low and Intermediate Risk)
NCT07056218 ·Status: NOT_YET_RECRUITING
-
Prediction of Lymph Node Metastasis in Patients With Thyroid Malignancy by a New Scale
NCT06286631 ·Status: RECRUITING
-
The Initial Management in Patients With Differentiated Thyroid Cancer in the Real World in China
NCT04857086 ·Status: UNKNOWN
-
Study of the Anti-angiogenesis Agent AG-013736 in Patients With Metastatic Thyroid Cancer
NCT00094055 ·Status: COMPLETED ·Phase: PHASE2
-
The Evaluation of the Diagnostic Properties of Intra-operative In-situ Thyroglobin Levels of Cervical Lymph Nodes, in the Discrimination Between Benign and Malignant Lymph Nodes in Thyroid Cancer: a Prospective Multicentre Study.
NCT02602717 ·Status: UNKNOWN ·Phase: NA
-
Study Of AG-013736 In Patients With 131I-Refractory Thyroid Cancer
NCT00389441 ·Status: COMPLETED ·Phase: PHASE2
-
Thyroxine Replacement Therapy After Lobectomy for Low-risk Papillary Thyroid Carcinoma
NCT06087068 ·Status: RECRUITING ·Phase: PHASE2
-
Review of Multimodality Management of Anaplastic Thyroid Cancer
NCT00280852 ·Status: COMPLETED
-
Extent of Central Lymph Node Dissection in Papillary Thyroid Microcarcinoma
NCT01149161 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Studies on Tumors of the Thyroid
NCT00001160 ·Status: RECRUITING
-
Use of an In Vivo Optical Probe to Discriminate Benign From Malignant Thyroid Nodules
NCT01401855 ·Status: COMPLETED
-
Taiwanese Anaplastic Thyroid Cancer Registry
NCT07138261 ·Status: NOT_YET_RECRUITING
-
99mTc Sestamibi Scans In Thyroglobulin Positive Scan Negative Differentiated Thyroid Cancer (DTC) Patients
NCT03065218 ·Status: TERMINATED ·Phase: PHASE4
-
Iodine Nutrition Status and Clinical Characteristics of Thyroid Cancer
NCT06623500 ·Status: RECRUITING
-
Observational Study Analysing the Transcriptome and Mutational Status of Thyroid Carcinomas of Follicular Origin with Different Degrees of Malignancy
NCT06878534 ·Status: RECRUITING