Study of Human Adipose Tissue (LOSHAT)
NCT03675464 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1500
Last updated 2020-09-04
Summary
The investigators will study the influence of initial fat cell size/number and adipose function (in particular lipolysis) on weight development over very long time periods (years). By comparing investigations of fat biopsies or blood samples obtained at baseline, the investigators will determine the association between adipose morphology/function and changes in weight or development of metabolic complications (e.g. metabolic syndrome, glucose intolerance, type 2 diabetes, dyslipidemia and hypertension).
Conditions
- Weight Change, Body
- Weight Loss
- Weight Gain
- Lipolysis
- Adipose Tissue
- Human
- Obesity
- Type 2 Diabetes Mellitus
Sponsors & Collaborators
- collaborator OTHER
-
Karolinska University Hospital
lead OTHER
Principal Investigators
-
Peter Arner, MD, PhD · Karolinska University Hospital
-
Daniel P Andersson, MD, PhD · Karolinska University Hospital
-
Mikael Rydén, Md, PhD · Karolinska University Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-09-20
- Primary Completion
- 2022-12-31
- Completion
- 2023-12-31
Countries
- Sweden
Study Locations
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