MedTrace Logo

Cerebral-tissue Oxygen Balance Affected by Diabetes Mellitus

NCT03668301 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 148

Last updated 2018-09-24

No results posted yet for this study

Summary

The brain has high oxygen extraction, thus the regional cerebral tissue oxygen saturation (rSO2) is lower than the central venous oxygen saturation (ScvO2). The investigators hypothesized that diabetes widens the physiological saturation gap between ScvO2 and rSO2 (gSO2), and the width of this gap may vary during various phases of cardiac surgery. The investigators involve cardiac surgery patients with and without type 2 diabetes mellitus (T2DM) undergoing either off-pump coronary artery bypass (OPCAB) or other cardiac surgery necessitating cardiopulmonary bypass (CPB). rSO2 is measured by near-infrared spectroscopy (NIRS) and ScvO2 is determined simultaneously from central venous blood. rSO2 is registered before and after anesthesia induction and at different stages of the surgery.

Conditions

  • Diabetes Mellitus (D003920)
  • Cardiac Surgical Procedures (D006348)
  • Near-Infrared (D019265)

Sponsors & Collaborators

  • Hungarian Basic Research Council

    collaborator OTHER

  • Szeged University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-01-31
Primary Completion
2017-07-31
Completion
2017-07-31

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03668301 on ClinicalTrials.gov