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Human Leucocyte Antigen G and Chronic Heart Failure

NCT03655925 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2019-04-17

No results posted yet for this study

Summary

The Human leukocyte antigen G (HLA-G) is a non-classical, major histocompatibility complex class I (MHC-I) protein that modulates the immune response, inhibiting it in most cases. Physiologically expressed in the cells of some tissues, it increases in inflammatory reactions. Inflammation appears to play an important role in the development of chronic heart failure. This study aims to evaluate the levels of soluble HLA-G in patients with heart failure and to investigate the relationships between HLA-G and other clinical-functional parameters of the disease. Investigators hypothesize that the plasma levels of HLA-G could correlate with the clinical status of heart failure and could provide indications on patient's prognosis.

Conditions

Interventions

DIAGNOSTIC_TEST

plasmatic HLA-G

plasmatic HLA-G by blood sample

Sponsors & Collaborators

  • Piera Boschetto

    lead OTHER

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-10-11
Primary Completion
2019-03-31
Completion
2019-03-31

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03655925 on ClinicalTrials.gov