is the Sclerostin Marker of Chronic Periodontitis
NCT03639636 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2018-08-21
Summary
Reviewed literature suggests that sclerostin will inhibit the bone formation and ultimately leads to chronic periodontitis. Estimation of Sclerostin levels in the serum of periodontitis patients before and after intervention could explore the effectiveness of therapy and also give a more detailed insight into its diagnostic and prognostic potential as a biomarker of periodontal disease.
Conditions
- Periodontitis
Interventions
- OTHER
-
non surgical and surgical periodontal therapy
scaling and root planing periodontal flap surgery
Sponsors & Collaborators
-
Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
lead OTHER
Principal Investigators
-
Jammula surya prasanna, mds · panineeya institute of dental sciences and research center
Study Design
- Purpose
- SCREENING
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 30 Years
- Max Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-06-01
- Primary Completion
- 2017-12-20
- Completion
- 2018-05-15
Countries
- India
Study Locations
More Related Trials
-
Quantification of Proteomes: L-plastin , Lipocalin and Adiponectin in Chronic Periodontitis and Diabetic Subjects
NCT03391349 ·Status: COMPLETED
-
Gingival Crevicular Fluid Levels of Sclerostin, Osteoprotegerin (OPG) and RANKL in Health, Disease and After Treatment
NCT02390479 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
GCF PLAP-1, Sclerostin and TNF-α Levels in Periodontitis
NCT05656989 ·Status: COMPLETED
-
Non-surgical Periodontal Therapy and Myo-inositol in Polycystic Ovary Syndrome Women Having Chronic Periodontitis
NCT02633462 ·Status: UNKNOWN ·Phase: PHASE2
-
Serum Lipid Levels and Lp-PLA2 in Chronic Periodontitis
NCT03041480 ·Status: COMPLETED
-
The Effect of Non-Surgical Periodontal Treatment on Bone Metabolism in Type 2 Diabetes and Systemically Healthy Individuals
NCT05862311 ·Status: COMPLETED ·Phase: NA
-
Osteoclast Impairment in Chronic Periodontitis by Regenerative Materials.
NCT03227367 ·Status: COMPLETED ·Phase: NA
-
SRP, Systemic Inflammation and Serum Bone Resorption Markers Premenopausal Women With Periodontitis and Low BMD
NCT04259242 ·Status: COMPLETED ·Phase: NA
-
EFFECT OF SCALING ON SERUM hsCRP LEVELS AND PERIODONTAL PARAMETERS IN SYSTEMICALLY HEALTHY YOUNG WOMEN WITH GINGIVITIS
NCT05639608 ·Status: UNKNOWN ·Phase: NA
-
Short-term Changes on C-Reactive Protein (CRP) Levels After Non-surgical Periodontal Treatment
NCT01433744 ·Status: COMPLETED ·Phase: NA
-
Relationship Between Periodontal Disease and Postmenopausal Osteoporosis
NCT07294105 ·Status: COMPLETED
-
Evaluation of Neopterin Levels in Pre and Post-menopausal Women With Periodontitis Following Non Surgical Therapy
NCT02357745 ·Status: UNKNOWN
-
Periostin and Non-Surgical Periodontal Treatment
NCT04332965 ·Status: COMPLETED ·Phase: NA
-
Development of a Molecular Diagnosing Platform for Relieving Periodontal Symptoms
NCT03345329 ·Status: COMPLETED
-
Bone Remodeling and Non-surgical Periodontal Therapy
NCT05636683 ·Status: UNKNOWN ·Phase: NA
-
Association Between Grade(B/C)of Stage III and IV Periodontitis and High Sensitivity C Reactive Protein Level in Serum and Oral Rinse Sample
NCT06997770 ·Status: NOT_YET_RECRUITING
-
Serum Levels of Vitamin D and IL8 in Patients With Periodontitis
NCT06306937 ·Status: COMPLETED
-
IL-34 Levels in Various Types of Periodontitis
NCT04223869 ·Status: COMPLETED ·Phase: NA
-
Impact of SRP on Bone Resorption and Systemic Inflammatory Markers in Postmenopausal Women With Periodontitis
NCT04261491 ·Status: COMPLETED ·Phase: NA
-
Quantification of CD163 Inflammatory Biomarker in Chronic Periodontitis and Diabetic Subjects
NCT03727035 ·Status: UNKNOWN
-
Serological Evaluation of 77A/G and 11A/12A Gene of MMP-13 in Periodontitis Affected and Healthy Individuals
NCT02423304 ·Status: UNKNOWN
-
Comparative Evaluation of Minimally Invasive Nonsurgical Periodontal Therapy Versus Conventional Subgingival Instrumentation
NCT05876455 ·Status: UNKNOWN ·Phase: NA
-
Impact of Supracrestal Tissue Attachment Dimension on Outcome of Scaling and Root Planing and Open Flap Debridement Procedure in Different Periodontal Phenotypes
NCT05696600 ·Status: UNKNOWN ·Phase: NA
-
Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis
NCT03270280 ·Status: UNKNOWN ·Phase: PHASE2
-
Estimation of Pentraxin3 and PGingivalis Levels in Patients With Knee Joint and Gum Diseases
NCT02503046 ·Status: COMPLETED