Umbilical Cord Milking in Non-Vigorous Infants

Summary

The investigators will conduct a study of non-vigorous term infants to determine if umbilical cord milking (UCM) results in a lower rate of NICU admissions than early clamping and cutting of the umbilical cord at birth for infants who need resuscitation.

Conditions

• Birth Asphyxia

Interventions

PROCEDURE

Umbilical Cord Milking

At delivery, the umbilical cord is grasped, and blood is pushed toward the infant 4 times before the cord is clamped. This procedure infuses a placental transfusion of blood into the infant and can be done in 15-20 seconds.

PROCEDURE

Early Cord Clamping

The umbilical cord is clamped within 60 seconds of delivery.

Sponsors & Collaborators

• Sharp Mary Birch Hospital for Women & Newborns

  collaborator OTHER

• Sharp Grossmont Hospital

  collaborator OTHER

• University of Utah

  collaborator OTHER

• University of Alberta

  collaborator OTHER

• Poznan University of Medical Sciences

  collaborator OTHER

• IWK Health Centre

  collaborator OTHER

• University of California, Davis

  collaborator OTHER

• Loma Linda University

  collaborator OTHER

• George Washington University

  collaborator OTHER

• Providence Hospital

  collaborator OTHER

• Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

  collaborator NIH

• Sharp HealthCare

  lead OTHER

Principal Investigators

• Anup Katheria, MD · Sharp HealthCare

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

CROSSOVER

Eligibility

Min Age

35 Weeks

Max Age

42 Weeks

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-01-05

Primary Completion

2021-06-01

Completion

2023-09-26

Countries

• United States
• Canada
• Poland

Study Locations