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Defining the Genetic Etiology of Alzheimer's Disease in the Faroe Islands

NCT03628404 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2022-03-17

No results posted yet for this study

Summary

The investigators established the Faroese Alzheimer's Cohort with the aim to unravel genetic and environmental factors that influence the risk and/or susceptibility of Alzheimers disease (AD). It is believed the Faroese population represents a unique opportunity due to its characteristics as a geographic, environmental and genetic isolate with a homogeneous genetic background and founder effects. It has an 'engaged' population with superbly detailed genealogy going 400 years back, unfettered patient access to health care, traditionally high participation rates in research and low probability of losing subjects to follow-up, and presents a unique opportunity to more readily identify genetic and environmental factors involved in AD.

The specific aims of this project are:

1. Enrolment of patients with AD, incl.1st degree family members of selected familial patients and age and gender matched control subjects.
2. Detailed genealogical investigation of patients with Alzheimer's disease
3. Identify genes influencing risk and/or susceptibility of AD in the Faroese population

Conditions

Sponsors & Collaborators

  • Faroese Hospital System

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-09-01
Primary Completion
2025-01-01
Completion
2025-01-01

Countries

  • Faroe Islands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03628404 on ClinicalTrials.gov