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Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries

NCT03580889 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 138

Last updated 2018-08-16

No results posted yet for this study

Summary

A study to compare between intravenous atropine and glycopyrrolate in preventing spinal anesthesia induced hypotension in patients undergoing major lower limb orthopedic surgeries. Hypotension is the most common complication in spinal anesthesia that can be life threatening. If this can be prevented patients comfort can be increased and satisfaction as well.

Conditions

  • Lower Extremity Fracture

Interventions

DRUG

Atropine

Comparison between atropine, glycopyrrolate and Normal Saline

DRUG

Glycopyrrolate

Comparison between glycopyrrolate, atropine and Normal saline

DRUG

Normal Saline Flush, 0.9% Injectable Solution

Comparison between Normal saline, atropine and glycopyrrolate

Sponsors & Collaborators

  • B.P. Koirala Institute of Health Sciences

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
FACTORIAL

Eligibility

Min Age
16 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-09-15
Primary Completion
2018-09-30
Completion
2018-09-30

Countries

  • Nepal

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03580889 on ClinicalTrials.gov