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Modeling and Closed-loop Control of Depth of Anaesthesia

NCT03569839 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2026-05-11

No results posted yet for this study

Summary

The study evaluates the effect of anaesthetic agents to depth of anaesthesia. An improved PK-PD model wil be developed that will provide the basis for understanding the mechanisms, simulating various scenarios and developing algorithms for better and safer administration of anaesthetic agents.

Conditions

  • The Focus is to Develop a Closed-loop Control System for Anaesthesia in Vitroretinal Surgery, Surgery Due to Expansive Processes in Head, and Long-term Sedation

Interventions

DRUG

Propofol

Patients undergoing surgery, TIVA (total intravenous anaesthesia)

Sponsors & Collaborators

  • University of Ljubljana

    lead OTHER

Principal Investigators

  • Gorazd Karer · University of Ljubljana

  • Iztok Potočnik · University Medical Centre Ljubljana

Eligibility

Min Age
20 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-09-14
Primary Completion
2027-12-31
Completion
2028-12-31
FDA Drug
Yes

Countries

  • Slovenia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03569839 on ClinicalTrials.gov