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Right Ventricular Echo Assessment in Mitral Valve Replacement

NCT03549052 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2018-06-07

No results posted yet for this study

Summary

Rheumatic heart disease remains a major health problem in developing countries. It is the most important sequel of rheumatic fever and occurs in about 30% of patients with rheumatic fever.Rheumatic heart disease presents with different degrees of pancarditis and associated valve failure. Involvement of the mitral leaflets can cause mitral regurgitation (MR) or stenosis and eventually can lead to heart failure. Mitral repair or replacement is therefore recommended before left ventricular (LV) dysfunction develops.

Study Objectives/Specific Aims Overall Goal: To determine the benefit the patient with pulmonary hypertension will get from mitral valve replacement as regard function improvement and remodeling of the right ventricle.

* Objective1: Identify risk factors that are predictive of outcomes.(Type and severity of Mitral valve pathology , severity of pulmonary hypertension, tricuspid regurge, preoperative RV dysfunction)
* Objective2: Determine the value of management strategies (Mitral valve replacement in pulmonary hypertension i.e. : decrease RV pressure overload and enhance RV remodeling)
* Objective3: Assessment of the outcomes clinically \& Echocardiographically : postoperative results during hospital stay and follow up (short term up to 3 months).

Conditions

  • Right Ventricular Dysfunction
  • Rheumatic Heart Disease

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Ahmed M. EL_Minshawy, Professor · Assiut University

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-06-01
Primary Completion
2019-12-30
Completion
2020-01-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03549052 on ClinicalTrials.gov