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Identifying PARDS Endotypes

NCT03539783 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 76

Last updated 2024-03-18

No results posted yet for this study

Summary

Pediatric acute respiratory distress syndrome (PARDS) is a severe and diffuse lung injury that is a common cause of admission and mortality in the pediatric intensive care unit (PICU). PARDS can be secondary to many different causes, and there are few therapies that have been shown beneficial in PARDS. This study seeks to identify important PARDS subtypes using gene expression profiling of bronchial epithelial cells from control and PARDS subjects.

Conditions

  • Respiratory Distress Syndrome
  • Respiratory Distress Syndrome, Adult

Interventions

DIAGNOSTIC_TEST

Respiratory epithelial cell brushing

At specified time points, nasal brushings will be performed to obtain RNA.

Sponsors & Collaborators

  • Society of Critical Care Medicine

    collaborator OTHER

  • Children's Hospital Medical Center, Cincinnati

    lead OTHER

Principal Investigators

  • Stephen M Standage, MD · Children's Hospital Medical Center, Cincinnati

Eligibility

Min Age
1 Month
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-04-01
Primary Completion
2022-08-11
Completion
2022-09-05

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03539783 on ClinicalTrials.gov