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Use of Simplified Lung Ultrasound Score for Predicting ICU Outcomes in Patients with Acute Respiratory Failure

NCT06678035 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 72

Last updated 2024-11-07

No results posted yet for this study

Summary

This study aims to

Primary Aims:

Verify the predictability of the PLIS at admission in predicting major clinical outcomes including:

* ICU mortality (or discharge) and time to death (or discharge)
* Escalation of ventilatory support antibiotic therapy or supportive medications (inotropes, steroids, sedation, neuromuscular blockers).

Secondary Aims:

* Determine the correlation between initial PLIS and the degree of disease severity (as evaluated per SOFA and APACHE II scores)
* Determine the correlation between initial PLIS and partial pressure of oxygen in arterial blood (PaO2) to Fraction of inspired oxygen (FiO2): PaO2/FiO2
* Explore the potential association between the type of ventilatory support, ventilatory settings and PLIS at different time points.
* Verify whether the site of consolidation (anterior vs. posterior lung zones) can reliably predict mortality in in ALI patients.
* Determine the correlation between the PLIS score and the degree of ALI as quantified by CT of the chest (whenever a CT study is available) at the time of admission.

Conditions

  • Pneumnia
  • Chest Infection
  • Critically-ill Patients Admitted to the ICU for Acute Respitatory Failure, Regardless the Aetilogy

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Eligibility

Min Age
18 Days
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-11-20
Primary Completion
2025-10-01
Completion
2025-10-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06678035 on ClinicalTrials.gov