Characterisation of Human B Cell Maturation in Response to Vaccination
NCT03535779 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 16
Last updated 2018-06-20
Summary
This study is an exploratory single site sample collection study at St Mary's hospital campus, Imperial College London. Sixteen participants scheduled to receive routine immunizations for Td/IPV (group 1) and HBsAg (group 2) will be recruited overall. Eights participants will be allocated to group 1 and eights participants to group 2 depending on their immunisation regime.
Conditions
Interventions
- BIOLOGICAL
-
The Hepatitis B virus, is a double stranded DNA virus that prevents Hepatitis B in the population
- BIOLOGICAL
-
Tetanus Toxoid
The Tetanus vaccine, also known as tetanus toxoid (Td/IVP), is an inactive vaccine used to prevent tetanus in the population
Sponsors & Collaborators
-
Imperial College London
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-03-06
- Primary Completion
- 2017-06-15
- Completion
- 2018-03-13
Countries
- United Kingdom
Study Locations
More Related Trials
-
Persistence of the Immune Response to Hepatitis B in 4-6 Years Old Children Previously Vaccinated With DTPa-HBV-IPV/Hib
NCT00335881 ·Status: COMPLETED ·Phase: PHASE4
-
Persistence of the Immune Response to Hepatitis B in 7-9 Years Old Children Previously Vaccinated With DTPa-HBV-IPV/Hib
NCT00356564 ·Status: COMPLETED ·Phase: PHASE4
-
Hepatitis B Challenge Dose in Adults (V232-059-10)
NCT01251276 ·Status: COMPLETED ·Phase: PHASE3
-
Understanding Poor Vaccine Responses to Hepatitis B Vaccination
NCT04674462 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Evaluate Immune Response Approximately 5 to 6 Years After Receiving Different Formulations of GSK Bio Hep B Vaccine
NCT00329576 ·Status: COMPLETED ·Phase: PHASE4
-
Long-term Persistence of Immunity Against Hepatitis B in 7-8 Years Old Children After Hepatitis B Vaccination.
NCT00519649 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Evaluate the Persistence of the Cellular and Humoral Immune Response Following Vaccinations With GlaxoSmithKline (GSK) Biologicals' Candidate Vaccines Containing HBsAg and Different Adjuvants in Healthy Adult Volunteers
NCT02153320 ·Status: COMPLETED ·Phase: PHASE1
-
A Blood Collection Study to Assess the Immunogenicity of Nationally Authorized Homologous COVID-19 Booster Vaccines Among Adult Vaccinees.
NCT05710289 ·Status: WITHDRAWN
-
Immune Response to Hepatitis B Virus Booster Vaccination After 20-23 Years
NCT02166671 ·Status: TERMINATED ·Phase: NA
-
A Study to Evaluate the Reactogenicity, Safety, and Immunogenicity of the Third Generation Hepatitis B Vaccine
NCT02692170 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Pilot Study: Gene Expression Profiling of Immune Response to HBV Vaccination in Healthy Volunteers
NCT02055365 ·Status: COMPLETED ·Phase: NA
-
Development of Read-outs in Healthy, Hepatitis B Virus Naive Adults Vaccinated With the Hepatitis B Surface Antigen (HBsAg) in Combination With a GlaxoSmithKline (GSK) Biologicals' Adjuvant System
NCT01777295 ·Status: COMPLETED ·Phase: PHASE2
-
Persistence of Immunity Against Hepatitis B in 12-13 Year Old Adolescents After Infant Hepatitis B Vaccination
NCT00984139 ·Status: COMPLETED ·Phase: PHASE4
-
VaxTeen Hepatitis B Vaccine Booster Study
NCT00144313 ·Status: COMPLETED ·Phase: PHASE4
-
The Immunogenicity and Safety of 60mcg/30mcg Recombinant Hepatitis B Vaccines in People Who Failed to Respond to Routine Administration of Hepatitis B Vaccines
NCT01203319 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Study of Evaluating Safety and Immunogenicity of 10µg/0.5ml Hepatitis B Vaccine
NCT02152709 ·Status: COMPLETED ·Phase: PHASE3
-
Persistence of Hepatitis B Antibody Levels & Immune Response to a Hepatitis B Vaccine Challenge
NCT00411697 ·Status: COMPLETED ·Phase: PHASE4
-
A Randomized,Parallel-group Clinical Trial of Hepatitis B Vaccine With Different Dosages and Schedules in Healthy Adults
NCT02203357 ·Status: COMPLETED ·Phase: PHASE4
-
A Study on the Safety and Immune Response of AS37 Together With Hepatitis B Antigen in Adults Aged 18-45 Years
NCT05561673 ·Status: COMPLETED ·Phase: PHASE1
-
Hepatitis B Vaccine Clinical Trial
NCT00000583 ·Status: COMPLETED ·Phase: PHASE3
-
Hepatitis B Antibody Persistence and Immune Response to Hepatitis B Vaccine Challenge in Previously Vaccinated Children
NCT01333813 ·Status: COMPLETED ·Phase: PHASE4
-
Immunosenescence and Hepatitis B Virus (HBV) Vaccine Efficacy in Chronic Renal Disease Patient
NCT02375711 ·Status: TERMINATED ·Phase: NA
-
Immunogenicity & Reactogenicity of Various Formulations of Recombinant Hepatitis B Vaccine With Different Adjuvants
NCT00697125 ·Status: COMPLETED ·Phase: PHASE2
-
Protectivity and Safety Following Recombinant Hepatitis B Vaccine
NCT03919578 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Clinical Trial of Recombinant Hepatitis B Vaccine (Hansenula Polymorpha, 10μg)
NCT04075201 ·Status: COMPLETED ·Phase: PHASE1