Investigation of Antipsoriatic Effects of UVB-induced Synthesis of 1alpha, 25-Dihydroxyvitamin D3 (1alpha, 25(OH)2D3, Calcitriol)in Keratinocytes of Psoriatic Skin, Using Cytochrom-P(CYP)Inhibitor Ketokonazol
NCT00678756 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2010-06-08
Summary
Exploration of antipsoriatic effects of UVB-therapy +/- CYP-inhibitor Ketokonazol on affected psoriatic skin
Conditions
- Psoriasis Vulgaris
Interventions
- DRUG
-
Ketokonazol 2% cream
twice a day at 2 times,2 out of 5 areas have to be treated for 4 weeks/7 days a week
- RADIATION
-
UVB-radiation 311nm
3 out of 5 areas are radiated for 4 weeks every MO/DI/DO/FR starting MED orientated, intensified everytime 0,03 J/qcm
Sponsors & Collaborators
-
Technische Universität Dresden
lead OTHER
Principal Investigators
-
Gottfried Wozel, Prof. Dr.med · Department of Dermatology, Medical Faculty, Technical University Dresden, Germany
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-03-31
- Primary Completion
- 2009-10-31
- Completion
- 2009-12-31
Countries
- Germany
Study Locations
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