Dental Restorations Effect on Oxidative Status of the Gingival Crevicular Fluid

Summary

The goal of the study was to ascertain the influence of dental caries and teeth position as well as the type and amount of the applied dental materials (DMs) on the oxidative stress (OS) status in gingival crevicular fluid (GCF).

Conditions

• Pharmacological Action

Interventions

PROCEDURE

Amalgam placement

Before the Amg was sealed GCF was taken, and then taken again on the 7th and 30th days after the applied treatment.

PROCEDURE

Tetric EvoCeram placement

Before the TEC was sealed GCF was taken, and then taken again on the 7th and 30th days after the applied treatment.

PROCEDURE

Beautifil placement

Before the BF was sealed GCF was taken, and then taken again on the 7th and 30th days after the applied treatment.

PROCEDURE

Zinc phosphate cement placement

Before the ZPhC was sealed GCF was taken, and then taken again on the 7th and 30th days after the applied treatment.

PROCEDURE

Zinc polycarboxylate cement placement

Before the ZPoC was sealed GCF was taken, and then taken again on the 7th and 30th days after the applied treatment.

PROCEDURE

Glass ionomer cement placement

Before the GIC was sealed GCF was taken, and then taken again on the 7th and 30th days after the applied treatment.

Sponsors & Collaborators

• University of Belgrade

  collaborator OTHER

• Ervin Taso

  lead OTHER

Principal Investigators

• Mirjana M Djukic, PhD, Pharm. · University of Belgrade

• Danilo V Vojvodic · Military Medical Academy, Belgrade

Study Design

Allocation

NON_RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2016-10-31

Primary Completion

2017-09-30

Completion

2017-11-30

Countries

• Serbia

Study Locations