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Effects of DIammine SIlver Fluoride on Tooth Sensitivity

NCT01063530 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 144

Last updated 2010-02-05

No results posted yet for this study

Summary

The purpose of the study is to confirm the clinical effectiveness and safety of topical diammine silver fluoride (DASF) as a tooth desensitizer in adulst by comparing it to the application of sterile water.

The study will be conducted in two different sites in Peru. Participantes will be 144 adults who will have at least one vital maxillary or mandibular cuspid or premolar with a cervical defect on the buccal surface and clinical hypersensitivity in response to air. Subjects will be randomly assigned to a topical application of DAS or sterile water.

The reduction of pain (sensitivity) using a 100 mm VAS, will be determined. Safety will be also determined by evaluating the gingival condition (erythema, white changes, ulceration, staining) before and ater the application of the products. The evaluation times will be 24 hours and 7 days.

Conditions

  • Dental Sensitivity
  • Gingival Condition

Interventions

DEVICE

DIammine SIlver fluoride

Application of Diammine SIlver Fluoride in cervical lesions

DEVICE

DIstilled water

Application of distilled water in cervical lesions

Sponsors & Collaborators

Principal Investigators

  • Peter Milgrom, DDS · University of Washington

  • Jorge L Castillo, DDS MS · Universidad Peruana Cayetano Heredia

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-02-28
Primary Completion
2010-03-31
Completion
2010-04-30

Countries

  • Peru

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01063530 on ClinicalTrials.gov