Prospective Study in Pelvic Radiotherapy Patients
NCT00220181 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2005-09-22
Summary
Symptoms such as diarrhoea and abdominal discomfort are common side effects of radiotherapy for tumours in the pelvis and usually occur within 2 weeks of starting treatment. Once the course of radiotherapy has been completed these symptoms usually subside, but in some patients they may continue and sometimes cause significant problems.
It is not clear what processes are occurring to trigger such symptoms. There are a number of possibilities and we would like to investigate these further. If we can identify specific reasons for symptoms being worse in one patient compared to another, then we can try to either prevent or treat these. The aim of this study is to look for differences in the way that the bowel adapts to radiotherapy in patients who do and those who don't experience bowel symptoms during their course of radiotherapy.
Conditions
- Gynaecological, Urological or Rectal Cancer
Sponsors & Collaborators
-
Royal Marsden NHS Foundation Trust
lead OTHER
Principal Investigators
-
Jervoise Andreyev · Imperial College London
Eligibility
- Min Age
- 0 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-04-30
- Completion
- 2005-09-30
More Related Trials
-
Fecal Microbiota Transplantation for Radiation Enteritis
NCT03516461 ·Status: RECRUITING ·Phase: NA
-
Dosimetric Limitation of Pelvic Bone and Peritoneal Space in Rectal Cancer Patients During Chemoradiotherapy
NCT05688033 ·Status: UNKNOWN ·Phase: NA
-
Palliative Short-Course Radiotherapy in Rectal Cancer
NCT02639403 ·Status: COMPLETED ·Phase: PHASE2
-
Predicting RadIotherapy ReSponse of Rectal Cancer With MRI and PET
NCT02233374 ·Status: COMPLETED ·Phase: NA
-
The Impact of Patient Positioning and Use of Belly Board on Small Bowel and Urinary Bladder Volume Irradiated in Patients Receiving Radiotherapy for Rectal Cancer: A Prospective Phase II Study
NCT01142713 ·Status: UNKNOWN ·Phase: PHASE2
-
Low-Fiber Diet or High-Fiber Diet in Preventing Bowel Side Effects in Patients Undergoing Radiation Therapy for Gynecological Cancer, Bladder Cancer, Colorectal Cancer, or Anal Cancer
NCT01170299 ·Status: COMPLETED ·Phase: NA
-
Maintenance Chemotherapy After Neoadjuvant Chemoradiation Therapy for Distal Rectal Cancer
NCT01613469 ·Status: TERMINATED ·Phase: PHASE2
-
Endoscopically-delivered Purastat to Treat Bleeding Caused by Radiation Proctopathy
NCT04918758 ·Status: COMPLETED ·Phase: NA
-
Prospective Assessment of Symptoms and Quality of Life in Rectal Cancer Patients Receiving Chemo-Radiotherapy
NCT00414232 ·Status: COMPLETED
-
Study of Short Course Radiation Therapy for Elderly Patients With Rectal Cancer
NCT04139967 ·Status: TERMINATED ·Phase: NA
-
Rectal Study: Value of Repeated FDG-PET-CT Scans in Rectal Cancer
NCT00576563 ·Status: COMPLETED ·Phase: NA
-
Preoperative Chemoradiation Versus Short Term Radiation Alone With Delayed Surgery for Stage II and III Resectable Rectal Cancer
NCT00597311 ·Status: UNKNOWN ·Phase: PHASE3
-
Proton Radiotherapy for Upper Gastrointestinal Malignancies
NCT01449864 ·Status: COMPLETED ·Phase: NA
-
Study of High-Dose-Rate Endorectal Brachytherapy (HDRBT) in the Treatment of Locally Advanced Low Rectal Cancer
NCT01226979 ·Status: COMPLETED ·Phase: NA
-
Radiation-induced Diarrhoea During Curative EBRT of Prostate and Rectal Cancer
NCT05684432 ·Status: COMPLETED
-
Lateral Lymph Node Dissection After Neoadjuvant Chemo-radiation in Advanced Low Rectal Cancer
NCT02614157 ·Status: TERMINATED ·Phase: NA
-
Predictors of Tumor Response and of Radiation Therapy Side Effects in Patients With Gastrointestinal Cancers
NCT01445327 ·Status: TERMINATED
-
Personalized Dietary Intervention in Managing Bowel Dysfunction and Improving Quality of Life in Stage I-III Rectosigmoid Cancer Survivors
NCT03063918 ·Status: COMPLETED ·Phase: NA
-
The Role of Short Course of Palliative Radiation in Metastatic Cancer Rectum
NCT06521827 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Postoperative Hypofractionated Radiation in Cervical and Endometrial Tumours: Phase II Study
NCT05857631 ·Status: RECRUITING ·Phase: NA
-
A Randomized Controlled Trial of Five - Flavor Sophora Flavescens Enteric - Coated Capsules for Radiation - Induced Proctitis After Pelvic Radiotherapy
NCT07053761 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Pulsed Low Dose Rate Radiation Therapy for Gastric Cancer Patients With Peritoneal Metastasis
NCT03061162 ·Status: UNKNOWN ·Phase: NA
-
A Real-World Study of Fecal Transplants for Cancer Therapy Side Effects
NCT07319364 ·Status: RECRUITING ·Phase: PHASE1
-
Radioisotope and Fluorescence Guidance in Rectal Cancer
NCT05336643 ·Status: UNKNOWN ·Phase: NA
-
Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers
NCT02222844 ·Status: RECRUITING ·Phase: NA