A Pragmatic Trial of An Adaptive eHealth HIV Prevention Program for Diverse Adolescent MSM

Summary

This pragmatic trial of an HIV prevention program focuses on HIV risk-reduction in men who have sex with men (MSM) ages 13-18. The design is a three-tiered, internet-based HIV prevention intervention series that uses a sequential multiple assignment randomized trial (SMART) to track adolescent MSM reporting varying degree of sexual risk.The program package includes: (1-low risk) a universally-delivered, brief, online sexual health education program designed for sexual and gender minority youth regardless of whether they are sexually active (Queer Sex Ed); (2-middle risk) a more intensive online intervention designed for diverse AMSM engaging in HIV transmission risk behaviors (Keep It Up!), and (3-high risk) the most intensive is a motivational interviewing (MI) intervention that will be delivered by MI therapists via online videochat (Young Men's Health Project).

Conditions

• Hiv
• Adolescent Behavior
• Sex, Safe

Interventions

BEHAVIORAL

Queer Sex Ed

Comprehensive sexual health education program condition (Informational)

BEHAVIORAL

Keep It Up

Culturally/situation-relevant HIV-prevention experimental condition (Motivational/behavioral)

BEHAVIORAL

Keep It Up-Control

HIV knowledge control condition, attention-matched to KIU (Informational)

BEHAVIORAL

Young Men's Health Project

Motivational enhancement video interviewing condition (Motivational/behavioral)

Sponsors & Collaborators

• National Institute on Minority Health and Health Disparities (NIMHD)

  collaborator NIH

• Northwestern University

  lead OTHER

Principal Investigators

• Brian Mustanski, PhD · Northwestern University

• Maggie Matson, MPH · Northwestern University

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Model

SEQUENTIAL

Eligibility

Min Age

13 Years

Max Age

18 Years

Sex

MALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2018-04-18

Primary Completion

2021-12-12

Completion

2021-12-12

Countries

• United States

Study Locations