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Comparison of Single Intra-articular Injection of Hyruan-One With Hylan G-F 20 in Knee Osteoarthritis

NCT03484091 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 276

Last updated 2025-09-22

No results posted yet for this study

Summary

We compare the efficacy of intra-articular injection of Hyruan-One with Hylan G-F 20 and placebo (NSS) controlled in a double-blind RCT.

Conditions

Interventions

DRUG

Hyruan-One

single dose intra-articular injection

DRUG

Hylan G-F 20

single dose intra-articular injection

DRUG

Normal saline

single dose intra-articular injection

Sponsors & Collaborators

  • Thammasat University

    lead OTHER

Principal Investigators

  • Nattapol Tammachote, MD · Thammasat University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-04-01
Primary Completion
2023-06-27
Completion
2023-12-31

Countries

  • Thailand

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03484091 on ClinicalTrials.gov