PACAP27 Headache Properties in Migraine Without Aura Patients
NCT03471039 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2019-01-24
Summary
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a signaling molecule, localized in sensory and parasympathetic perivascular nerves fibres. PACAP exists i to functional iso-forms Pituitary adenylate cyclase-activating polypeptide-38 (PACAP38) and PACAP27.
Conditions
- Migraine Without Aura
Interventions
- DRUG
-
PACAP27
Infusion of PACAP27 over 20 minutes.
- DRUG
-
Saline
Infusion of Saline over 20 minutes.
Sponsors & Collaborators
-
Danish Headache Center
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- HEALTH_SERVICES_RESEARCH
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-08-30
- Primary Completion
- 2018-08-30
- Completion
- 2018-09-30
Countries
- Denmark
Study Locations
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