PACAP Induced Migraine Attacks in Patients With High and Low Genetic Load
NCT02158221 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32
Last updated 2015-02-10
Summary
The investigators hypothesized that migraine without patients with many genetic loci associated with migraine (high genetic load) would be more sensitive and get provoked more migraine attacks by PACAP compared to patients with few genetic loci associated with migraine (low genetic load).
Conditions
- Migraine Without Aura
Interventions
- DRUG
-
PACAP
Pituitary adenylate cyclase-activating polypeptide (PACAP)
Sponsors & Collaborators
-
Danish Headache Center
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-06-30
- Primary Completion
- 2014-11-30
- Completion
- 2014-12-31
Countries
- Denmark
Study Locations
More Related Trials
-
Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic Migraine
NCT00541736 ·Status: COMPLETED ·Phase: NA
-
Headache Inducing Effect of Cromakalim in Migraine Patients
NCT03228355 ·Status: COMPLETED ·Phase: NA
-
PACAP38 Induced Headache, Migraine and Flushing in Patients With Migraine
NCT03881644 ·Status: COMPLETED ·Phase: NA
-
Migraine Induction Properties of PACAP-38 After Eptinezumab in Migraine Without Aura Patients.
NCT05635604 ·Status: COMPLETED ·Phase: NA
-
Induction of Migraine Attacks With Aura Using Pituitary Adenylate Cyclase Activating Polypeptide-38
NCT07342296 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
The Hemodynamic Effects of PACAP38 After Glibenclamide Administration in Healthy Volunteers
NCT04960657 ·Status: COMPLETED ·Phase: NA
-
Cabergoline as a Preventive Treatment for Chronic Migraine
NCT05525611 ·Status: COMPLETED ·Phase: NA
-
Calcitonin Gene Related Peptide-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2.
NCT00358839 ·Status: COMPLETED ·Phase: NA
-
Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2
NCT00257985 ·Status: COMPLETED ·Phase: NA
-
PACAP27 Headache Properties in Migraine Without Aura Patients
NCT03471039 ·Status: COMPLETED ·Phase: NA
-
Calcitonin Gene-related Peptide in Familial Hemiplegic Migraine (FHM) and Migraine With Aura (MA)
NCT00687947 ·Status: COMPLETED ·Phase: NA
-
Migraine Inducing Effect of Levcromakalim in Patients With Migraine With Aura
NCT04905654 ·Status: COMPLETED ·Phase: NA
-
Headache Inducing Effect of Levcromakalim in Migraine With Aura Patients
NCT04012047 ·Status: COMPLETED ·Phase: NA
-
Induction of Migraine Attacks With Aura Using Calcitonin Gene-Related Peptide
NCT07021859 ·Status: RECRUITING ·Phase: NA
-
A Retrospective Chart Review to Evaluate Diagnosis and Treatment of Chronic Migraine and Headache
NCT01946126 ·Status: COMPLETED
-
Natriuretic Peptide's Headache Inducing Characteristics and Effects on the Cerebral Blood Flow
NCT01637662 ·Status: COMPLETED ·Phase: NA
-
Hypersensitivity to Opening of ATP-Sensitive Potassium Channels in Post-Traumatic Headache
NCT05243953 ·Status: COMPLETED ·Phase: NA
-
Headache Inducing Effect of NN414 in Migraine Patients
NCT04744129 ·Status: UNKNOWN ·Phase: NA
-
The Effects of Levcromakalim in Patients With Cluster Headache
NCT05093582 ·Status: COMPLETED ·Phase: NA
-
The Effect of PACAP27 on the Extra- and Intracerebral Arteries Assessed by Magnetic Resonance Angiography (MRA) on Healthy Volunteers
NCT03560024 ·Status: COMPLETED ·Phase: NA
-
Clinical Characteristics and Pathophysiology of Post-Traumatic Headache
NCT03791515 ·Status: COMPLETED ·Phase: NA
-
The Role of Inflammation and Vasodilatation in PACAP38-induced Headache Using MRI on Healthy Subjects
NCT03585894 ·Status: COMPLETED ·Phase: NA
-
The Evolution and Management of Migraine Recurrence Beyond 24 Hours
NCT00754611 ·Status: COMPLETED
-
CGRP-induced Migraine Attacks in Patients Who Have Tried Anti-CGRP Monoclonal Antibody Treatment
NCT03481400 ·Status: UNKNOWN ·Phase: NA
-
PGI2 Induced Headache and Cerebral Haemodynamics in Healthy Volunteers
NCT00291395 ·Status: TERMINATED ·Phase: PHASE1