Generation of an Induced Pluripotent Stem (iPS) Cell Bank Immune Matched to a Majority of the US Population
NCT03434808 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 19
Last updated 2020-07-15
Summary
The purpose of this study is to develop a collection of iPS cells called a bank ("Bank") that are immune-matched to a large percentage of the US population by containing the most common HLA haplotypes in the US population.
Conditions
- iPS Cell Manufacture and Banking
Interventions
- OTHER
-
Whole Blood Donation
Study subjects will provide 250ml whole blood donation for the manufacture and banking of iPS cells.
Sponsors & Collaborators
-
Cellular Dynamics International, Inc. - A FUJIFILM Company
collaborator UNKNOWN -
Center for International Blood and Marrow Transplant Research
lead NETWORK
Principal Investigators
-
Dennis Confer, MD · National Marrow Donor Program
-
Amanda Mack, PhD · Cellular Dynamics International, Inc. - A FUJIFILM Company
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 61 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-01-13
- Primary Completion
- 2018-08-17
- Completion
- 2018-08-17
More Related Trials
-
HLA-Mismatched Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematological Malignancies
NCT00001748 ·Status: COMPLETED ·Phase: PHASE1
-
Kidney and Hematopoietic Cell Transplants Using a Regimen to Promote Hematopoietic Cell Engraftment
NCT04571203 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE1
-
Using T-Cell Alloreactivity and Chimerism to Guide Immunosuppression Minimization in Intestinal Transplantation
NCT04804891 ·Status: RECRUITING ·Phase: PHASE1
-
Immunologic Diagnostic Blood Test in Predicting Side-Effects in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Other Diseases
NCT00813501 ·Status: TERMINATED
-
Markers of Inflammation in Hematopoietic Stem Cell Transplant
NCT00579397 ·Status: COMPLETED
-
Microfluidics and Transcriptomics in Post Solid Organ Transplant Patients
NCT02776111 ·Status: TERMINATED
-
Investigating Cytokine Genes of Stem Cell Donors
NCT00353821 ·Status: COMPLETED
-
T Cells in Predicting Acute Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant
NCT00651716 ·Status: TERMINATED
-
T-cell and B-cell Depletion in Allogeneic Peripheral Blood Stem Cell Transplantation
NCT00306332 ·Status: TERMINATED ·Phase: PHASE3
-
Biospecimen Procurement for Immunological Landscape Studies Following Hematopoietic Cell Transplantation
NCT04428918 ·Status: WITHDRAWN
-
Cell Free DNA Profiling As a Tool to Monitor Clinically-Relevant Events in Allogeneic Hematopoietic Stem Cell Transplantation
NCT06715046 ·Status: RECRUITING
-
The HOPE Biobank Resource (BMT CTN 2402 HOPE)
NCT07227155 ·Status: NOT_YET_RECRUITING
-
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies
NCT02579967 ·Status: RECRUITING ·Phase: PHASE2
-
A Clinical Study to Investigate Interferon Gamma (IFNɣ) Signature in Patients Post HSCT and in Patients With Impaired HSC Proliferation Pre-transplant
NCT04494061 ·Status: TERMINATED
-
Long-Term Follow-up of People Undergoing Hematopoietic Stem Cell Transplantation
NCT03000244 ·Status: RECRUITING
-
Early Detection of Infectious and Noninfectious Lung Diseases Following Allogeneic Hematopoietic Stem Cell Transplantation
NCT06093867 ·Status: RECRUITING
-
The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen
NCT01890486 ·Status: RECRUITING
-
Improving Blood Stem Cell Collection and Transplant Procedures
NCT01517035 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes
NCT00001405 ·Status: RECRUITING
-
Immune Mediated Disorders After Allogeneic Hematopoietic Cell Transplantation
NCT01206309 ·Status: COMPLETED
-
In-Vitro Studies in Depletion of Haplotype Mismatched Alloreactive T Cells
NCT00731705 ·Status: WITHDRAWN
-
Kinetic Analysis of Immune Cells in Blood and Chronic Graft-Versus-Host Disease-Affected Tissues After Allogeneic Hematopoietic Cell Transplantation
NCT07235501 ·Status: NOT_YET_RECRUITING
-
A Study of iMSC for the Prevention of Acute Graft-versus-host Disease After Allogeneic Hematopoietic Stem Cell Transplantation
NCT06949267 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Prospective Assessment of Allogeneic Hematopoietic Cell Transplantation in Patients With Myelofibrosis
NCT02934477 ·Status: RECRUITING
-
Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants
NCT00106925 ·Status: RECRUITING