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Perception of Stressful Social Stimuli After Trauma Exposure.

NCT03421587 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2019-02-15

No results posted yet for this study

Summary

Post-traumatic stress disorder is associated with altered processing of sensory stimuli. The clinical phenotype PTSD has predominantly been described for the visual and auditory sensory modalities. However, PTSD symptoms such as intrusive memories are often evoked by olfactory and tactile cues in the environment. Moreover, little is known about whether aberrant responses to social olfactory and tactile stimuli are also present in a subclinical population.The purpose of this study is to compare trauma-exposed subjects (e.g. childhood maltreatment) with non-exposed controls in the processing of olfactory and tactile stimuli. This sensory characterizations hold potential to identify potential biomarkers for the course of trauma-related disorders and to inform trauma therapies focusing on sensory integration.

Conditions

  • Post-traumatic Stress Disorder

Interventions

BEHAVIORAL

Processing of social olfactory and tactile stimuli

Processing of social olfactory and tactile stimuli in trauma-exposed individuals and controls is examined using functional magnetic resonance imaging.

Sponsors & Collaborators

  • University Hospital, Bonn

    lead OTHER

Principal Investigators

  • René Hurlemann, PhD, MD, MSc · Department of Psychiatry, University of Bonn, Germany

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-11-30
Primary Completion
2018-12-31
Completion
2018-12-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03421587 on ClinicalTrials.gov