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Sedation Strategies for Diagnostic Bronchoscopy

NCT03406533 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2019-06-12

No results posted yet for this study

Summary

Diagnostic bronchoscopy is an invasive procedure performed to diagnose respiratory diseases. But pain has been complained by most of the patients receiving such procedures. Sedation or anesthesia was required by both of the patients and bronchoscopists. Unfortunately, no consensus has been made upon the sedation strategies. Multiple sedation approaches have been applied, such as midazolam and fentanyl, remifentanil and propofol, dexmedetomidine and propofol. The present study was designed to compare these protocols in sedation for diagnostic bronchoscopy.

Conditions

  • Bronchoscopy
  • Sedation

Interventions

DRUG

Midazolam

Midazolam is used as a common medication for sedation in all groups.

DRUG

Dexmedetomidine

Dexmedetomidine is used for sedation in bronchoscopy with less impact on respiration.

DRUG

Remifentanil

Remifentanil is used for analgesia to prevent bronchoscopy induced cough.

DRUG

Fentanyl

Fentanyl is another opioid drug used for analgesia to prevent bronchoscopy induced cough.

DRUG

Propofol

Propofol is used for sedation with high efficacy but more side effect on respiration than dexmedetomidine.

Sponsors & Collaborators

  • Shanghai Zhongshan Hospital

    collaborator OTHER

  • Ruijin Hospital

    collaborator OTHER

  • Shanghai Pulmonary Hospital, Shanghai, China

    collaborator OTHER

  • Changhai Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-02-01
Primary Completion
2018-03-30
Completion
2018-03-31

Countries

  • China

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03406533 on ClinicalTrials.gov