Study of Apatinib Combined With TACE in Advance Hepatocellular Carcinoma
NCT03398122 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 248
Last updated 2018-01-12
Summary
the purpose of this study is to evaluate the efficacy and safety of aptinib in patients with advanced HCC
Conditions
Interventions
- PROCEDURE
-
TACE
epirubicin 30-60mg was injected into the blood supply artery of the tumor ,Embolization was subsequently performed with granules of gelatin sponge particles.
- DRUG
-
Apatinib
a molecular targeted anti-tumor drugs,small molecule vascular endothelial growth factor receptor 2 inhibitor
Sponsors & Collaborators
-
Tianjin Medical University Cancer Institute and Hospital
lead OTHER
Principal Investigators
-
Zhi Guo, MD · Tianjin Medical University Cancer Institute and Hospital
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-11-14
- Primary Completion
- 2018-10-01
- Completion
- 2019-04-01
Countries
- China
Study Locations
More Related Trials
-
A Study of Second-line Treatment With Apatinib for Advanced Intrahepatic Cholangiocarcinoma
NCT03521219 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Second-line Treatment With Apatinib After TACE in Advanced Hepatocellular Carcinoma Patients
NCT02727309 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Study of Apatinib in Patients With Advanced Hepatocellular Carcinoma
NCT01192971 ·Status: COMPLETED ·Phase: PHASE2
-
Treatment Patients With Pulmonary Metastasis of Liver Cancer With Apatinib Combination With TACE: a Clinical Study
NCT02702323 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
A Study of TACE Combined With Camrelizumab Plus Rivoceranib (Apatinib) in Patients With Incurable Hepatocellular Carcinoma
NCT05320692 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study of Apatinib for Advanced Hepatocellular Carcinoma Patients After First-line Treatment Failure
NCT02772029 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Study of TAE+HAIC Combined With Camrelizumab and Apatinib in the Treatment of Advanced Hepatocellular Carcinoma
NCT06363825 ·Status: RECRUITING ·Phase: PHASE2
-
TACE Combined With Camrelizumab and Apatinib in Intermediate and Advanced Hepatocelluar Carcinoma
NCT04559607 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Combine Apatinib Mesylate With PD-1 Antibody SHR-1210 for HCC With High Risk of Recurrence After Radical Resection
NCT03839550 ·Status: UNKNOWN ·Phase: PHASE2
-
ET 140202 -T Cell Combined With TAE or Sorafenib in the Treatment of Liver Cancer
NCT03965546 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Single Arm, Prospective, Multicenter Clinical Study of TACE With Adebrelimab and Bevacizumab for Unresectable Hepatocellular Carcinoma
NCT05970666 ·Status: RECRUITING ·Phase: PHASE2
-
TACE Combined With Camrelizumab and Apatinib in the Treatment of Advanced Liver Cancer
NCT05550025 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Second-line Treatment With Apatinib in Patients With Advanced Intrahepatic Cholangiocarcinoma
NCT03251443 ·Status: COMPLETED ·Phase: PHASE2
-
Anlotinib Combined With TACE in Hepatocellular Carcinoma Patients at High Risk of Post Surgery Recurrence
NCT04213118 ·Status: UNKNOWN ·Phase: PHASE2
-
Anlotinib for Hepatocellular Carcinoma
NCT04954521 ·Status: UNKNOWN
-
Hepatocellular Carcinoma (HCC) Transarterial Chemoembolisation (TACE) +Axitinib
NCT01352728 ·Status: COMPLETED ·Phase: PHASE2
-
TACE Combined With Immune Checkpoint Inhibitors for Liver Malignant Tumors
NCT06487663 ·Status: RECRUITING ·Phase: NA
-
Lenvatinib Combined With TACE to Prevent the Recurrence in High-risk Patients With Hepatocellular Carcinoma
NCT03838796 ·Status: UNKNOWN ·Phase: NA
-
TACE, Sorafenib and PD-1 Monoclonal Antibody in the Treatment of HCC
NCT04518852 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Apatinib After Systemic Therapy in Patients With Hepatocellular Carcinoma(AHELP)
NCT02329860 ·Status: COMPLETED ·Phase: PHASE3
-
A Real-world Study of Donafenib Combined With TACE-based Treatment in Patients With Unresectable HCC
NCT05205629 ·Status: UNKNOWN
-
TACE Combined With Anti-PD-1 Antibody in Patients With Advanced Hepatocellular Carcinoma: Study on Efficacy and Immune Microenvironment
NCT07100405 ·Status: RECRUITING
-
TACE-HAIC Combined With TKIs and Immunotherapy Versus TACE Alone for Hepatocellular Carcinoma With PVTT
NCT05535998 ·Status: COMPLETED
-
Evaluation Effectiveness and Safety of (cTACE or DEB-TACE + FOLFOX Regimen HAIC) Combined With Camrelizumab and Apatinib Mesylas in the Treatment of Advanced Hepatocellular Carcinoma
NCT04479527 ·Status: UNKNOWN ·Phase: PHASE2
-
Axitinib For The Treatment Of Advanced Hepatocellular Carcinoma
NCT01210495 ·Status: COMPLETED ·Phase: PHASE2