Single Arm, Prospective, Multicenter Clinical Study of TACE With Adebrelimab and Bevacizumab for Unresectable Hepatocellular Carcinoma
NCT05970666 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 71
Last updated 2024-02-28
Summary
To evaluate the efficacy and safety of TACE combined with adebrelimab and bevacizumab transformation in unresectable hepatocellular carcinoma
Conditions
- Adebrelimab
- Hepatocellular Carcinoma
- Transformation
- Bevacizumab
- TACE
Interventions
- DRUG
-
TACE with adebrelimab and bevacizumab
TACE treatment once; Adebrelimab: 20mg/kg, every 3 weeks (21 days); Bevacizumab; 15mg/kg, every 3 weeks (21 days);
Sponsors & Collaborators
-
Jiangsu HengRui Medicine Co., Ltd.
collaborator INDUSTRY -
The First Affiliated Hospital of Xiamen University
lead OTHER
Principal Investigators
-
Jianbo Chen · The First Affiliated Hospital of Xiamen University
-
Feng Ye · The First Affiliated Hospital of Xiamen University
-
congren Wang · Quanzhou First Hospital
-
Qinghe Cai · Affiliated Hospital of Putian University
-
Jiafei Chen · Putian First Hospital
-
Yongzhong Wang · Sanming Second Hospital
-
Feng Lin · Ningde Mindong Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-11-15
- Primary Completion
- 2026-11-15
- Completion
- 2026-11-15
Countries
- China
Study Locations
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