A Real-world Study of Donafenib Combined With TACE-based Treatment in Patients With Unresectable HCC
NCT05205629 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2022-03-23
Summary
This study is a prospective, single-center, observational real-world study. It is planned to enroll 150 patients with unresectable hepatocellular carcinoma treated with Donafenib combined with TACE-based treatment, so as to observe and evaluate the efficacy and safety of Donafenib combined with TACE-based treatment in patients with unresectable HCC.
Conditions
- Hepatocellular Carcinoma
- Donafenib
Interventions
- DRUG
-
Donafenib combined with TACE
Donafenib(200mg bid po) combined with TACE
Sponsors & Collaborators
-
Shanghai Zhongshan Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-01-30
- Primary Completion
- 2024-01-30
- Completion
- 2024-03-30
Countries
- China
Study Locations
More Related Trials
-
Donafenib Plus Sintilimab in Combination With TACE in Patients With Unresectable Hepatocellular Carcinoma
NCT05507632 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Study of Donafenib Combined With Tislelizumab in the Adjuvant Treatment of Primary HCC With High Risk of Recurrence
NCT05545124 ·Status: UNKNOWN ·Phase: PHASE2
-
TACE Combined With Lenvatinib for Unresectable Hepatocellular Carcinoma (Prolong)
NCT04560751 ·Status: UNKNOWN
-
The Treatment of Unresectable Liver Cancer With E-TACE Combined With Donafenib:A Prospective, Single-arm, Multicenter, Observational Study
NCT07180459 ·Status: NOT_YET_RECRUITING
-
TACE Combinated With Sorafenib in Treating Patients With Unresectable Hepatocellular Carcinoma
NCT01605734 ·Status: UNKNOWN ·Phase: PHASE2
-
TACE Combined With Lenvatinib for Unresectable Hepatocellular Carcinoma
NCT04490694 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study Evaluating the Efficacy and Safety of ZG005 in Combination With Donafenib or Bevacizumab in Patients With Advanced Hepatocellular Carcinoma
NCT06233994 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Postoperative Adjuvant Therapy of Donafenib for Hepatocellular Carcinoma
NCT06581315 ·Status: RECRUITING ·Phase: NA
-
Survival Analysis: TACE vs. Combination Therapy in HCC
NCT06261138 ·Status: COMPLETED
-
Primary Hepatobiliary Cancer Cohort of Central China
NCT05520801 ·Status: RECRUITING
-
TACE, Sorafenib and PD-1 Monoclonal Antibody in the Treatment of HCC
NCT04518852 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib Concomitantly Used With TACE (Transarterial Chemoembolization) in uHCC (Unresectable Hepatocellular Carcinoma) Patients in China
NCT01839630 ·Status: COMPLETED
-
Efficacy and Safety of Transarterial Therapies+Donafenib + Anti-PD-1 Antibody for uHCC: A Retrospective Real-world Study
NCT05638438 ·Status: UNKNOWN
-
TACE Combined With Camrelizumab and Apatinib in Intermediate and Advanced Hepatocelluar Carcinoma
NCT04559607 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
TACE+Tilelizumab+Sorafenib in the Treatment of BCLC Stage C HCC
NCT04992143 ·Status: UNKNOWN ·Phase: PHASE2
-
Donafenib Combined With Immunotherapy and Local Therapy for Unresectable Hepatocellular Carcinoma That Has Failed in Previous Therapy
NCT06496815 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Efficacy and Safety of Apatinib Combined With TACE in Patients With Hepatocellular Carcinoma
NCT03510416 ·Status: UNKNOWN ·Phase: PHASE2
-
TACE With or Without Sorafenib in Intermediate Stage Hepatocellular Carcinoma
NCT02529761 ·Status: UNKNOWN ·Phase: NA
-
Application of Integrated Proteomic and Serum Metabolomic Analysis in Assessing the Efficacy and Prognosis of TACE Combined With Targeted Immunotherapy in Unresectable Hepatocellular Carcinoma
NCT06540508 ·Status: ENROLLING_BY_INVITATION
-
TACE Plus Sorafenib Versus TACE Alone for Recurrent Intermediate Hepatocellular Carcinoma
NCT04103398 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of Donafenib in Patients With Advanced Hepatocellular Carcinoma
NCT02645981 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
TACE Combined With Lenvatinib and MWA in the Treatment of Locally Advanced Large Hepatocellular Carcinoma
NCT05555316 ·Status: UNKNOWN ·Phase: PHASE2
-
A Retrospective Study on the Treatment of Intermediate and Advanced Liver Cancer.
NCT06205732 ·Status: RECRUITING
-
Donafenib Plus Sintilimab for Advanced HCC
NCT05162352 ·Status: COMPLETED ·Phase: PHASE2
-
Hepatic Artery Infusion Chemotherapy Plus Donafenib in Patients With Hepatocellular Carcinoma After Surgery
NCT04962958 ·Status: UNKNOWN ·Phase: PHASE2